Unveiling the role of local metabolic constraints on the structure and activity of spiking neural networks. [PDF]
Jaras I +3 more
europepmc +1 more source
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Correction: Paired competing neurons improving STDP supervised local learning in spiking neural networks. [PDF]
Goupy G, Tirilly P, Bilasco IM.
europepmc +1 more source
Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui +8 more
wiley +1 more source
Dynamic spatio-temporal pruning for efficient spiking neural networks. [PDF]
Gou S +7 more
europepmc +1 more source
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source
Noise and Dynamical Synapses as Optimization Tools for Spiking Neural Networks. [PDF]
Garipova Y, Yonekura S, Kuniyoshi Y.
europepmc +1 more source
Ultrafast Multilevel Switching and Synaptic Behavior in a Planar Quantum Topological Memristor
Dry‐transferred Bi2Te3 layers enable a planar quantum topological memristor framework. In‐plane topological surface states facilitate ultrafast & low‐power operations. Coexisting analog and digital modes support current‐controlled multilevel states. PQTM exhibits 105 s retention, 103 cycles endurance, and reproducibility across 24 devices.
Mamoon Ur Rashid +12 more
wiley +1 more source
Three-stage hybrid spiking neural networks fine-tuning for speech enhancement. [PDF]
Abuhajar N +7 more
europepmc +1 more source
A nanoparticle‐engineered electrolyte‐gated memtransistor is introduced as a materials‐level strategy to overcome the intrinsic trade‐off between energy consumption and synaptic precision. By embedding aluminum nanoparticles at the oxide–electrolyte interface to modulate ion trapping dynamics, the device achieves stable multistate plasticity under ...
Jun‐Gyu Choi +4 more
wiley +1 more source

