Results 71 to 80 of about 52,867 (269)
Mechanisms of Zero-Lag Synchronization in Cortical Motifs [PDF]
, 2014 Zero-lag synchronization between distant cortical areas has been observed in a diversity of experimental data sets and between many different regions of the brain.
Breakspear, Michael +3 more
core +5 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Response nonlinearities in networks of spiking neurons
PLOS Computational Biology, 2019 ABSTRACTCombining information from multiple sources is a fundamental operation performed by networks of neurons in the brain, whose general principles are still largely unknown. Experimental evidence suggests that combination of inputs in cortex relies on nonlinear summation.
Sanzeni, Alessandro +2 more
openaire +5 more sources
Information capacity of a network of spiking neurons [PDF]
Physica A: Statistical Mechanics and its Applications, 2020 We study a model of spiking neurons, with recurrent connections that result from learning a set of spatio-temporal patterns with a spike-timing dependent plasticity rule and a global inhibition. We investigate the ability of the network to store and selectively replay multiple patterns of spikes, with a combination of spatial population and phase-of ...
Scarpetta, Silvia, de Candia, Antonio
openaire +3 more sources
A Neuron Model for FPGA Spiking Neuronal Network Implementation
Advances in Electrical and Computer Engineering, 2011 We propose a neuron model, able to reproduce the basic elements of the neuronal dynamics, optimized for digital implementation of Spiking Neural Networks. Its architecture is structured in two major blocks, a datapath and a control unit.
BONTEANU, G., TIGAERU, L.
doaj +1 more source
Modeling cortical synaptic effects of anesthesia and their cholinergic reversal.
PLoS Computational Biology, 2022 General anesthetics work through a variety of molecular mechanisms while resulting in the common end point of sedation and loss of consciousness. Generally, the administration of common anesthetics induces reduction in synaptic excitation while promoting
Bolaji P Eniwaye +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
High-Temperature, but Not High-Pressure, Conditions Alter Neuronal Activity
Journal of Pharmacological Sciences, 2009 .: We describe the effect of high pressure and high temperature on neuronal activity. Increased intracranial pressure is generally a pathological sign observed in intracerebral hemorrhage, brain edema, and brain tumor, yet little is known about how the ...
Mika Mizunuma +4 more
doaj +1 more source
VIOLA - A multi-purpose and web-based visualization tool for neuronal-network simulation output
, 2018 Neuronal network models and corresponding computer simulations are invaluable tools to aid the interpretation of the relationship between neuron properties, connectivity and measured activity in cortical tissue.
Carde, Corto +5 more
core +4 more sources
Advanced Functional Materials, EarlyView.This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han +17 more
wiley +1 more source