Results 81 to 90 of about 1,596,273 (306)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Spin-relaxation times exceeding seconds for color centers with strong spin-orbit coupling in SiC

, 2019
Spin-active color centers in solids show good performance for quantum technologies. Several transition-metal defects in SiC offer compatibility with telecom and semiconductor industries.
Danny van Hien (17513160), N. T. Son (3931271), Caspar H. van der Wal (9160832), Freddie Hendriks (14381694), Tom Bosma (14413560), Ivan G. Ivanov (1352076), Carmem M. Gilardoni (17513157), Alexandre Ellison (17513163), Björn Magnusson (664978)   +8 more
core   +1 more source

Nonvolatile magnetization switching in a single-layer magnetic topological insulator

Communications Physics, 2023
Magnetization in a ferromagnetic layer could be manipulated by the spin-orbit torque whose generation commonly relies on the spin-orbit coupling from the adjacent heavy-metal layer within the bilayer.
Huimin Sun, Yizhou Liu, Daiqiang Huang, Yu Fu, Yu Huang, Mengyun He, Xuming Luo, Wenjie Song, Yang Liu, Guoqiang Yu, Qing Lin He   +10 more
doaj   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Symmetry exploitation in closed-shell coupled-cluster theory with spin-orbit coupling

, 2011
Symmetry exploitation in closed-shell Coupled-cluster theory with spin-orbit couplingIn the present work, we report exploitation of spatial symmetry in calculations of ground state energy and analytic first derivatives of closed-shell molecules based on ...
Yang, Dong-Dong, FanWang, Tu, Zheyan, Wang, Fan, Guo, Jingwei   +4 more
core   +1 more source

Spin-Orbit-Induced Transport in Metals and Superconductors [PDF]

, 2013
This thesis is devoted to the theoretical study of spin-orbit-induced transport in diffusive normal metals and superconductors. The spin-orbit interaction plays a vital role in the aspiring field of spintronics, which aims to utilize the electron spin ...
Sadjina, Severin
core   +1 more source

Spin-orbit coupling induced splitting of Yu-Shiba-Rusinov states in antiferromagnetic dimers

Nature Communications, 2021
The influence of spin-orbit coupling on the hybridization of Shiba states in dimers of magnetic atoms on superconducting surfaces remains unexplored.
Philip Beck, Lucas Schneider, Levente Rózsa, Krisztián Palotás, András Lászlóffy, László Szunyogh, Jens Wiebe, Roland Wiesendanger   +7 more
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

Arthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source

Enhanced spin–orbit coupling in core/shell nanowires

Nature Communications, 2016
Spin-orbit coupling underlies many important spintronic concepts, and is strongly influenced by crystal symmetry. Here, the authors demonstrate a strong enhancement of spin-orbit coupling in core/shell semiconductor nanowires induced by the large ...
Stephan Furthmeier, Florian Dirnberger, Martin Gmitra, Andreas Bayer, Moritz Forsch, Joachim Hubmann, Christian Schüller, Elisabeth Reiger, Jaroslav Fabian, Tobias Korn, Dominique Bougeard   +10 more
doaj   +1 more source

Supercurrent diode effect and magnetochiral anisotropy in few-layer NbSe2

Nature Communications, 2022
The supercurrent diode effect was recently observed in a Nb/V/Ta superlattice thin film with Rashba-type spin-orbit coupling. Here, the authors observe this effect in few-layer NbSe2 crystals driven by valley-Zeeman-type spin-orbit coupling and find that
Lorenz Bauriedl, Christian Bäuml, Lorenz Fuchs, Christian Baumgartner, Nicolas Paulik, Jonas M. Bauer, Kai-Qiang Lin, John M. Lupton, Takashi Taniguchi, Kenji Watanabe, Christoph Strunk, Nicola Paradiso   +11 more
doaj   +1 more source