Results 21 to 30 of about 402 (235)
Vojnotehnički Glasnik, 2017 Aerospace as a whole, primarily aviation and planes, for a short time after 1903, greatly advance the frontiers of human activity. Initially, unsafe "flying device" the plane, has become a factor in loose resolving wars and one of the reliable means
Branko B. Bilbija
doaj +1 more source
Aerodynamic Characteristics of a Spinning Delta Wing
JOURNAL OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES, 2003 The experiments of a delta wing’s spin phenomena were conducted at the low speed wind tunnel of Nagoya University with its exit test section inclined vertically. The spin rate of the delta wing in the free rotation mode was measured as well as surface pressure distributions on the spinning delta wing.
Takafumi Yamada, Yoshiaki Nakamura
openaire +2 more sources
Learning Aircraft Spin Dynamics from Measurement Data Using Hankel DMDc with Error in Variables
AerospaceAircraft spin, a nonlinear phenomenon dominated by unsteady aerodynamics, is difficult to predict. This article proposes a novel approach using Hankel Dynamic Mode Decomposition with Control (HDMDc) to identify an aircraft plant model for spin motion ...
Balakumaran Swaminathan +1 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Wind-Induced Responses of Nonlinear Angular Motion for a Dual-Spin Rocket
AerospaceFin-stabilized guided rockets exhibit ballistic characteristics such as low initial velocity, high flight altitude, and long flight duration, which render their impact point accuracy and flight stability highly susceptible to the influence of wind.
Jianwei Chen +2 more
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Aerodynamic characteristics of an ogive-nose spinning projectile
Sādhanā, 2018 This work experimentally investigates the Robins–Magnus effect on a 5-caliber spinning projectile at a low subsonic Mach number of 0.1 corresponding to a Reynolds number of 3.2 × 105 based on the model length. The model configuration tested was a cylinder with spherically blunt tangent ogive nose portion.
J LIJIN, T J S JOTHI
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source