Results 41 to 50 of about 10,426 (300)

Paradoxical popups: Why are they hard to catch?

open access: yes, 2008
Even professional baseball players occasionally find it difficult to gracefully approach seemingly routine pop-ups. This paper describes a set of towering pop-ups with trajectories that exhibit cusps and loops near the apex.
A. Terry Bahill   +7 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Kesediaan pelajar dari aspek kemahiran teknikal terhadap pembentukan kebolehkerjaan di Kolej Vokasional Wilayah Selatan [PDF]

open access: yes, 2015
Graduan yang menganggur terus menjadi masalah yang semakin meruncing di Malaysia. Terdapat majikan yang menganggap kompetensi akademik sahaja tidak mencukupi dan mula meminta institusi pendidikan tinggi untuk menghasilkan graduan yang dilengkapi ...
Hanafi., Suhaili
core  

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Wind-Induced Responses of Nonlinear Angular Motion for a Dual-Spin Rocket

open access: yesAerospace
Fin-stabilized guided rockets exhibit ballistic characteristics such as low initial velocity, high flight altitude, and long flight duration, which render their impact point accuracy and flight stability highly susceptible to the influence of wind.
Jianwei Chen   +2 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

The Kinematics of Falling Pterocymbium Tinctorium Seeds

open access: yesInternational Scholastic Journal of Science, 2020
Pterocymbium tinctorium (Thai:ปออีเก้ง, Por-Ae-Keang ) is a tree found in Thailand and other Southeast Asian countries. The fruit, containing a single seed with an attached single wing extending to one side and a hollow boat-shaped structure that braces
Akio Ikegami   +3 more
doaj  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

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