Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings [PDF]
Pediatric DiscoverySpina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished ...
Ethan S. Wong +13 more
doaj +3 more sources
Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study [PDF]
Frontiers in UrologyObjectivesTo characterize the estimated prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida through a large claims database.MethodsThis retrospective claims study used the MarketScan® databases from 2008 to
Nyemkuna Fortingo +7 more
doaj +4 more sources
Spina Bifida: A Review of the Genetics, Pathophysiology and Emerging Cellular Therapies [PDF]
Journal of Developmental Biology, 2022 Spina bifida is the most common congenital defect of the central nervous system which can portend lifelong disability to those afflicted. While the complete underpinnings of this disease are yet to be fully understood, there have been great advances in ...
Abd-Elrahman Said Hassan +4 more
openalex +2 more sources
Neonatal and infant mortality associated with spina bifida: A systematic review and meta-analysis.
PLoS ONE, 2021 ObjectivesA systematic review was conducted in high-income country settings to analyse: (i) spina bifida neonatal and IMRs over time, and (ii) clinical and socio-demographic factors associated with mortality in the first year after birth in infants ...
Peter Ho +4 more
doaj +2 more sources
Prevalence of Spina Bifida among Newborns in Africa: A Systematic Review and Meta-Analysis
Scientifica, 2020 Spina bifida is an abnormal closure of the neural tube during the fourth week of development. It is the major cause of fetal loss and considerable disabilities in newborns.
Mohammed Oumer +3 more
doaj +2 more sources
Prevention of spina bifida: folic acid intake during pregnancy in Gulu district, northern Uganda [PDF]
The Pan African Medical Journal, 2015 INTRODUCTION: the intake of folic acid before conception and during the first trimester of pregnancy can prevent spina bifida. This paper describes folic acid intake in women in Gulu district in northern Uganda.
Femke Bannink +4 more
doaj +4 more sources
Fetal spina bifida: What we tell the parents [PDF]
Prenatal Diagnosis, 2020 Worldwide, about 150 000 infants are born with spina bifida yearly, making this condition one of the most common fetal central nervous system anomalies compatible with life.
Lara Gotha +10 more
openalex +2 more sources
Transition to adulthood: Experience of Japanese youth with spina bifida [PDF]
Health Care TransitionsBackground: Emerging adults with spina bifida have complex developmental and health care needs. Improvement in healthcare means there is greater interest in understanding and supporting the transition needs of children with spina bifida to adulthood ...
Shiho Murayama +2 more
doaj +2 more sources
Neural Regeneration Research, 2019 O6-methylguanine DNA methyltransferase (MGMT), a DNA repair enzyme, has been reported in some congenital malformations, but it is less frequently reported in neural tube defects.
He-Nan Zhang +5 more
doaj +2 more sources
Motor-cognitive interaction in adults with spina bifida: dual-task effects. [PDF]
Spinal CordBendt M +9 more
europepmc +3 more sources