Results 71 to 80 of about 87,442 (288)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Simultaneous tubeless supine percutaneous nephrolithotomy and cystolitholapaxy in a patient with spina bifida

Urology Case Reports
Spina bifida is a congenital condition that often leads to significant urological complications, including an increased risk of kidney and bladder stones.
Zoltán Kiss, Gyula Drabik, János Dócs, Tibor Flaskó   +3 more
doaj   +1 more source

Premature Neural Progenitor Cell Differentiation Into Astrocytes in Retinoic Acid-Induced Spina Bifida Rat Model

Frontiers in Molecular Neuroscience, 2022
During embryonic spinal cord development, neural progenitor cells (NPCs) generate three major cell lines: neurons, oligodendrocytes, and astrocytes at precise times and locations within the spinal cord.
Marc Oria, Marc Oria, Bedika Pathak, Zhen Li, Kenan Bakri, Kara Gouwens, Maria Florencia Varela, Kristin Lampe, Kendall P. Murphy, Kendall P. Murphy, Chia-Ying Lin, Jose L. Peiro, Jose L. Peiro   +12 more
doaj   +1 more source

Sexualidade nas lesões medulares congénitas: spina bifida [PDF]

, 2008
A sexualidade é uma vertente complexa que contempla múltiplas questões biopsicossociais. Em indivíduos com alterações do desenvolvimento do tubo neural, nomeadamente spina bifida, a construção da sexualidade está ainda pouco estudada.
Garrett, Ana, Martins, Fernando, Teixeira, Zélia   +2 more
core   +1 more source

Crash sign: new first‐trimester sonographic marker of spina bifida

Ultrasound in Obstetrics and Gynecology, 2019
To describe a new first‐trimester sonographic sign, the ‘crash sign’, associated with fetal open spina bifida, and to evaluate its clinical usefulness in the first‐trimester diagnosis of spina bifida.
F. Ushakov, A. Sacco, E. Andreeva, S. Tudorache, T. Everett, A. David, P. Pandya   +6 more
semanticscholar   +1 more source

Psychological and behavioral correlates of health anxiety and other anxiety phenomena in adolescence—A cross‐sectional study in the Copenhagen Child Cohort 2000

JCPP Advances, EarlyView.
Abstract Background Health anxiety (HA) is characterized by impairing worry about being or becoming seriously ill. This cross‐sectional study aimed to explore psychological and behavioral correlates of HA compared to other anxiety phenomena in adolescents, that is, with respect to depression, physical symptoms, bodily dissatisfaction, health‐related ...
Charlotte Steen Duholm, Davíð R. M. A. Højgaard, Kaare Bro Wellnitz, Eva Ørnbøl, Per Hove Thomsen, Martin Køster Rimvall, Charlotte Ulrikka Rask   +6 more
wiley   +1 more source

Recipients of electric-powered indoor/outdoor wheelchairs provided by a National Health Service: A cross-sectional study [PDF]

, 2013
This is the post-print version of the final paper published in Archives of Physical Medicine and Rehabilitation. The published article is available from the link below.
Albright, Andrew O. Frank, Arthanat, Arva, Auger, Brandt, British Society of Rehabilitation Medicine, Burnfield, Cooper, Cooper, Davies, Dicianno, Evans, Evans, Fitzgerald, Frank, Frank, Frank, Frank, Gibson, Giesbrecht, Greer, Johnson, Karmarkar, Kenneson, Kirby, Lindsay, Lofqvist, Lord, Lorraine H. De Souza, May, Murphy, Muscular Dystrophy Campaign, Richardson, Rodby-Bousquet, Sonenblum, Vignier, Ward, Warren, Washington, West, Westgren, Wiart   +42 more
core   +1 more source

Neurodevelopmental outcome of children with spina bifida aperta repaired prenatally vs postnatally: systematic review and meta‐analysis

Ultrasound in Obstetrics and Gynecology, 2019
To assess the neurodevelopmental outcome of children with spina bifida aperta (SBA) treated prenatally as compared to those treated postnatally.
A. Inversetti, A. Inversetti, L. V. D. Veeken, D. Thompson, K. Jansen, F. Calenbergh, L. Joyeux, J. Bosteels, J. Deprest   +8 more
semanticscholar   +1 more source

β3‐Adrenoceptor Agonists for Neurogenic Lower Urinary Tract Dysfunction: Evidence and Clinical Rationale for First‐Line Therapy

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To summarize current evidence on β3‐adrenoceptor agonists for managing neurogenic lower urinary tract dysfunction (NLUTD), focusing on their efficacy, safety, and clinical role in optimizing bladder storage and protecting upper tracts. Methods Evidence from randomized controlled trials, meta‐analyses, and observational studies in spinal ...
Sharon E. Fishberg, Rano Matta
wiley   +1 more source

Altered microRNA expression profiles in a rat model of spina bifida

Neural Regeneration Research, 2016
MicroRNAs (miRNAs) are dynamically regulated during neurodevelopment, yet few reports have examined their role in spina bifida. In this study, we used an established fetal rat model of spina bifida induced by intragastrically administering olive oil ...
Pan Qin, Lin Li, Da Zhang, Qiu-liang Liu, Xin-rang Chen, He-ying Yang, Ying-zhong Fan, Jia-xiang Wang   +7 more
doaj   +1 more source