Results 81 to 90 of about 20,453 (200)

A Transforaminal Endoscopic Surgical Technique for Treating Lumbar Disc Herniation in the Setting of Spina Bifida

open access: yesCase Reports in Neurological Medicine, 2020
Recent literature suggests that adult patients with spina bifida receive surgery for degenerative disc disease at higher rates than the general population.
Albert E. Telfeian   +5 more
doaj   +1 more source

Socio‐Ecological Factors of Physical Activity in Children and Adolescents With Down Syndrome: A Mixed‐Methods Systematic Review

open access: yesJournal of Intellectual Disability Research, Volume 70, Issue 7, Page 665-677, July 2026.
ABSTRACT Background Children and adolescents with Down syndrome (DS) are at risk of obesity due to a reduced level of physical activity (PA). PA in children and adolescents with DS is a multifaceted phenomenon that includes personal, relationship, community and other social factors.
Seung Hyeon Yang   +4 more
wiley   +1 more source

From Multiple Congenital Anomalies to Pituitary Gland Malformation: Wide Spectrum of Clinical Features in a Family With FOXA2 Variant

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1452-1457, June 2026.
ABSTRACT FOXA2 (hepatocyte nuclear factor‐3β, HNF‐3β) encodes a transcriptional activator involved in early embryogenesis, particularly in the patterning and differentiation of midline structures such as the neural tube, foregut, and pituitary gland. Its role in human pathogenesis was first suspected when patients with deletion of chromosome 20p11.2 ...
Christopher Connolly   +3 more
wiley   +1 more source

Predictors of long‐term outcome in open spina bifida

open access: yes
Developmental Medicine &Child Neurology, EarlyView.
Alison Poulton, Pippa Oakeshott
wiley   +1 more source

‘SOMS BrainSpace’: A digital serious game for undergraduate neuroscience

open access: yesAnatomical Sciences Education, Volume 19, Issue 6, Page 985-1007, June 2026.
Abstract Neuroanatomy is challenging for many undergraduates, requiring strong visuospatial skills and a deep understanding of complex concepts. This study developed and evaluated SOMS BrainSpace, a digital serious game for neuroanatomy education, using a mixed methods approach.
Anthony Tran   +3 more
wiley   +1 more source

Opportunities and Challenges for Surveillance of Congenital Anomalies in Sub‐Saharan Africa

open access: yesBirth Defects Research, Volume 118, Issue 6, June 2026.
ABSTRACT Introduction Congenital anomalies (CA) are ranked as the 3rd and 4th leading cause of neonatal and under‐5 mortality, respectively. Over 30% of infants born with a serious CA are found in sub‐Saharan Africa. Yet there are few robust epidemiological data on the burden and distribution of CA and associated mortality, disability, and morbidity ...
Emma Kalk   +18 more
wiley   +1 more source

Altered microRNA expression profiles in a rat model of spina bifida

open access: yesNeural Regeneration Research, 2016
MicroRNAs (miRNAs) are dynamically regulated during neurodevelopment, yet few reports have examined their role in spina bifida. In this study, we used an established fetal rat model of spina bifida induced by intragastrically administering olive oil ...
Pan Qin   +7 more
doaj   +1 more source

Synergistic Enhancement: Whole Wheat Substrate Improves Memory in Mice by Optimizing Folate Metabolism and Systemic Antioxidant Capacity

open access: yesFood Bioengineering, Volume 5, Issue 2, Page 244-258, June 2026.
ABSTRACT This study rigorously assessed the impact of folic acid‐fortified whole wheat products on mitigating mild liver injury caused by prolonged excessive folic acid consumption, improving folic acid bioavailability, and enhancing spatial cognitive functions in mice over a 48‐day intervention period.
Yan Qi   +3 more
wiley   +1 more source

Toxicological Evaluation of the Roots of Ficus pandurata Hance var. angustifolia Cheng

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Toxicological evaluation of the roots of Ficus pandurata Hance var. angustifolia Cheng for safe utilization. Two‐year‐old RFPH roots were prepared as an aqueous extract powder, with 1 g equivalent to 30 g of raw material. Acute oral toxicity, genotoxicity, teratogenicity, and 90‐day repeated‐dose oral toxicity tests were performed in SD rats and ICR ...
Yamin Chen   +12 more
wiley   +1 more source

Morphological Variants and Factors Associated With Neural Tube Defects at a Regional Referral Hospital

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Neural Tube Defects (NTDs) remain a significant public health concern, especially in low‐resource settings. This study investigated the morphological variants of NTDs and identified factors associated with their development among neonates at Mbarara Regional Referral Hospital (MRRH).
Benard Owere   +3 more
wiley   +1 more source

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