Results 101 to 110 of about 1,355,397 (313)

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Assessing the real benefits of surgery for degenerative lumbar spinal stenosis without instability and spondylolisthesis: a single surgeon experience with a mean 8-year follow-up [PDF]

, 2018
Background: The degenerative lumbar spinal stenosis is one of the most commonly treated spinal disorders in older adults; despite its increasing frequency, it is not yet clear what the most effective therapy might be.
Caruso, Riccardo, Lanciano, Tiziana, Martines, Valentina, Paolini, Sergio, Pesce, Alessandro, Piccione, Emanuele, Wierzbicki, Venceslao   +6 more
core   +2 more sources

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury. [PDF]

, 2010
Although axonal regeneration after CNS injury is limited, partial injury is frequently accompanied by extensive functional recovery. To investigate mechanisms underlying spontaneous recovery after incomplete spinal cord injury, we administered C7 spinal ...
Beattie, Michael S, Bresnahan, Jacqueline C, Brock, John H, Courtine, Gregoire, Edgerton, V Reggie, Ferguson, Adam R, Havton, Leif A, Jindrich, Devin L, Miller, Darren M, Nout, Yvette S, Rosenzweig, Ephron S, Roy, Roland R, Strand, Sarah C, Tuszynski, Mark H   +13 more
core  

Transplantation of olfactory ensheathing cells into spinal cord lesions restores breathing and climbing [PDF]

, 2003
One of the most devastating effects of damage to the upper spinal cord is the loss of the ability to breathe; patients suffering these injuries can be kept alive only with assisted ventilation. No known method for repairing these injuries exists.
Decherchi, P., Li, Y., Raisman, G.
core   +2 more sources

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Functional outcome of patients with spinal cord injury: rehabilitation outcome study [PDF]

, 1999
Objective: To increase our knowledge of neurological recovery and functional outcome of patients with spinal cord injuries in order to make more successful rehabilitation programmes based on realistic goals.Design: Descriptive analysis of data gathered ...
G A Mulder, Hussey RW, J W Groothoff, Lazar RB, M C Schönherr, Rogers JC, W H Eisma, Waters RL, Waters RL, Waters RL, Welch RD, World Health Organization, Yarkony GM   +12 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

EFFICACY OF INTRAMUSCULAR PHENYLEPHRINE FOR MAINTENANCE OF MATERNAL HEMODYNAMICS IN CAESAREAN SECTION UNDER SPINAL ANAESTHESIA

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the efficacy of intramuscular phenylephrine for maintenance of maternal hemodynamics in caesarean section under spinal anesthesia. Study Design: Case series.
Muhammad Saeed, Muhammad Musa, Muhammad Mubashir Khan, Sajjad Qureshi, Muhammad Hassan, Fayyaz Ahmad Ofri   +5 more
doaj  

Morphometric Analysis of Dry Typical Thoracic Vertebrae: A Cross sectional Study from Telangana, India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Morphometric measurements of dry typical thoracic vertebrae play an important role clinically in managing scoliosis, performing laminectomies, guiding pedicle screw fixation, and in designing spinal implants or prostheses for ...
BH Shiny Vinila, Masooma Begum, K Ephraim Vikram Rao, E Rajshekhar Reddy   +3 more
doaj   +1 more source