Results 131 to 140 of about 1,010,665 (307)

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Efficacy of Fampridine on Refractory Optic Neuritis in Neuromyelitis Optica Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) usually occur with acute refractory optic neuritis (ON). However, there is a lack of efficacious treatments to improve recovery. Since fampridine has been found to improve the prognosis of multiple sclerosis (MS) and MS‐related ON, it is necessary to explore the efficacy of fampridine ...
Hongxuan Wang, Wanru Chen, Xiangpen Li, Hengjian Lu, Chenguang Li, Xiaoni Zhang, Lulu Bu, Xiaoyu Xu, Qingyu Shen, Ying Peng   +9 more
wiley   +1 more source

A Retrospective Observational Study of Ephedrine Use in Hip Arthroplasty: Routine Practice at a Secondary Care Hospital in Romania

Clinics and Practice
Background and Objectives: The primary goal of the study is to analyze factors associated with spinal anesthesia-induced hypotension (SAIH), with a focus on ephedrine requirements in relation to patient characteristics and the type of intrathecal opioid ...
Erika Bimbo-Szuhai, Mihai Octavian Botea, Harrie Toms John, Adela Bostan Danciu, Pirvan Titus Razvan, Mihaela Gabriela Bontea, Mihai Pavel, Caius Salajan, Maria Viviana Rusu, Adrian Gheorghe Osiceanu, Iulia Codruta Macovei   +10 more
doaj   +1 more source

Spinal subdural tuberculous abscess

, 2000
Objectives: Spinal subdural abscess Is rare and only 45 cases have been described to date. In this report, we present an additional spinal subdural tuberculous abscess. Method: Tuberculous meningitis was diagnosed with clinical and laboratory findings in
Özates, M, Sari, I, Ü Özkan, Kemaloglu, S, I Sari, Özkan, Ü, S Kemaloglu, S Hos̨oglu, Hosoglu, S, M Özates̨   +9 more
core   +1 more source

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

Protection and Repair After Spinal Cord Injury: Accomplishments and Future Directions

, 2015
It was an honor for me to present the 2014 G. Heiner Sell Memorial Lecture at the annual American Spinal Injury Association (ASIA) meeting in San Antonio.
Dietrich, W. Dalton
core   +1 more source

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo, Claudia Dosi, Stefano Parravicini, Riccardo Zanin, Marta Cheli, Eleonora Giacopuzzi Grigoli, Amalia Canciello, Francesca Andreetta, Riccardo Masson, Silvia Bonanno, Stefania Marcuzzo, Lorenzo Maggi   +11 more
wiley   +1 more source

A STUDY OF POST OPERATIVE ANALGESIA AND ADVERSE EFFECTS PRODUCED BY INTRATHECAL NEOSTIGMINE, MORPHINE AND THEIR COMBINATION IN PATIENTS UNDERGOING ELECTIVE CAESAREAN SECTION UNDER SPINAL ANAESTHESIA

Pakistan Armed Forces Medical Journal, 2018
This is a double blind placebo controlled study of 120 patients conducted in the department of anesthesiology POF’s Hospital Wah Cantt: from October 2002 to April 2003 to evaluate the post operative analgesia and side effects of IT neostigmine, morphine
Muhammad Ishaque, Riaz Siddiqi, Shoaib Naiyar Hashmi, Azra Naseem   +3 more
doaj  

Continuous Thoracic Segmental Spinal Anesthesia for Ovarian Cystectomy in a Patient with Recurrent Perioperative Anaphylaxis: A Case Report

Bali Journal of Anesthesiology
Perioperative anaphylaxis is uncommon but potentially fatal, and subsequent anesthetic management is difficult when the responsible allergen remains unidentified.
Sohel Anjum, Richa Chandra, Roberto Starnari   +2 more
doaj   +1 more source

Effect of dural puncture epidural combined with programmed intermittent epidural bolus on labor analgesia in patients with gestational hypertension: a randomized controlled clinical trial

Frontiers in Medicine
BackgroundHypertensive disorders of pregnancy affect 5–10% of pregnancies and require the maintenance of hemodynamic stability while providing effective labor analgesia.
Binghui Zhang, Hongyang Zhang, Yuan Wu, Guofang Li, Shuxiang Liu, Kai Zhao   +5 more
doaj   +1 more source