Results 111 to 120 of about 81,152 (336)

Brachyury‐Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment

open access: yesAdvanced Science, EarlyView.
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong   +12 more
wiley   +1 more source

Lumbar tinea versicolor and spinal anaesthesia

open access: yesIDCases, 2019
Infection to the meningeal layer causing meningitis is one of the most feared complications of spinal anaesthesia. Anaesthetists will avoid spinal anaesthesia for those who are having skin infection at the puncture site.
Mohd Zulfakar Mazlan   +3 more
doaj  

Similar Effects of General and Spinal Anaesthesia on Perioperative Stress Response in Patients Undergoing Haemorrhoidectomy

open access: yesMediators of Inflammation, 2006
Surgery induces release of neuroendocrine hormones (cortisol), cytokines (interleukin-6: IL-6, tumour necrosis factor-α: TNF-α), acute phase proteins (C-reactive protein: CRP, leptin).
Unase Buyukkocak   +6 more
doaj   +1 more source

Efficiency of spinal anesthesia versus general anesthesia for lumbar spinal surgery: a retrospective analysis of 544 patients. [PDF]

open access: yes, 2017
BACKGROUND: Previous studies have shown varying results in selected outcomes when directly comparing spinal anesthesia to general in lumbar surgery. Some studies have shown reduced surgical time, postoperative pain, time in the postanesthesia care unit ...
Attiah, Mark A.   +9 more
core   +1 more source

BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates [PDF]

open access: yes, 2019
© 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Background: The marked increase in mis-use of prescription opioids has greatly affected our society. One potential solution is to develop improved analgesics which have
Cami-Kobeci, Gerta   +9 more
core   +4 more sources

EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways

open access: yesAdvanced Science, EarlyView.
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen   +12 more
wiley   +1 more source

Efficacy of different size Quincke spinal needles in reduction of incidence of Post-Dural Puncture Headache (PDPH) in Caesarean Section (CS). Randomized controlled study

open access: yesEgyptian Journal of Anaesthesia, 2017
Background: Regional analgesia first introduced in clinical practice by the German surgeon Karl August Bier (1898). Spinal, epidural or combined spinal and epidural anaesthesia became the first line of choice in obstetric surgery.
Emad Lotfy Mohammed   +1 more
doaj   +1 more source

Immunocompatible Elastomer With Enhanced Fibrous Capsule‐Resistance and Elasticity by Water‐Induced Surface Phase Reconfiguration.

open access: yesAdvanced Science, EarlyView.
This study introduces a strategy for engineering heterogeneous surface and bulk structures within a single material, termed phase‐separation and underwater reconfiguration‐enhanced (PURE) elastomers. These elastomers combine high bulk elasticity with enhanced immunocompatibility at the surface.
Xianchi Zhou   +10 more
wiley   +1 more source

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