Results 141 to 150 of about 85,514 (349)

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

Magnetically Responsive Piezoelectric Nanocapacitors Enhance Neural Recovery Following Spinal Cord Injury via Targeted Spinal Magnetic Stimulation

open access: yesAdvanced Science, EarlyView.
This study presents a novel “in vivo–in vitro” therapeutic strategy for spinal cord injury by leveraging magnetically responsive piezoelectric nanomaterials. These nanomaterials enable targeted delivery of localized electrical stimulation at the injury site through noninvasive external magnetic actuation, thereby promoting axonal regeneration and ...
Zhihang Xiao   +9 more
wiley   +1 more source

Efficacy of ultrasound-guided sacral erector spinae block in elective surgery. An up-to-date systematic review and meta-analysis of randomised controlled trials

open access: yesIndian Journal of Anaesthesia
Background and Aims: The sacral erector spinae plane block (SESPB) is emerging as a promising ultrasound-guided regional anaesthesia technique for postoperative pain management in various surgical procedures.
Eros Pilia   +5 more
doaj   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu   +6 more
wiley   +1 more source

Evaluation of spinal and epidural anaesthesia for day care surgery in lower limb and inguinoscrotal region

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2011
Background: Day care surgery is still in its infancy in India. Both regional and general anaesthesia can be used for this. Central neuraxial blocks are simple cheap and easy to perform.
Asha Gupta   +3 more
doaj  

Continuous spinal anaesthesia

open access: yesBritish Journal of Anaesthesia, 1998
N M, Denny, D E, Selander
openaire   +2 more sources

The Microbiota Shapes Central Nervous System Myelination in Early Life

open access: yesAdvanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch   +13 more
wiley   +1 more source

Radiation-induced lowered neurogenesis associated with shortened latency of inhibitory avoidance memory response [PDF]

open access: yes, 2011
The neural system is less sensitive to radiation than other late-responding organs and tissues such as the kidney and lung. The generation of new neurons in the adult mammalian brain has been documented in several works.
Azami, N.S.   +3 more
core  

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