Results 61 to 70 of about 40,161 (301)

Dural ectasia

Indian Journal of Anaesthesia, 2014
Dural ectasia is one of the likely causes of incomplete or failed spinal anaesthesia. Its association with diseases like Marfans syndrome, neurofibromatosis, osteogenesis imperfecta, vertebral fracture, postopertative adhesions, trauma etc., is often ...
Neha Gupta, Veena Gupta, Abhishake Kumar, Gaurav Kumar   +3 more
doaj   +1 more source

The effects of unilateral and bilateral spinal anaesthesia on hemodynamic parameters in patients surgically treated for inguinal hernia: Hemodynamic parameters and spinal anesthesia [PDF]

Serbian Journal of Anesthesia and Intensive Therapy, 2016
Introduction: Conventional bilateral spinal anaesthesia is commonly used for surgical treatment of inguinal hernia because it causes fast development of block with relatively small dosage of local anaesthetic; furthermore, it is easily administered ...
Milosavljević Snežana, Pavlović Aleksandar, Trpković Slađana, Vujović Maja, Špadijer-Mirković Cveta   +4 more
doaj   +1 more source

Effects of preoperative methoxamine on blood loss and haemodynamic variables during transurethral prostatic resection under spinal anaesthesia

, 1994
Thirty-six patients who presented for transurethral prostatic resection were allocated randomly to one of two groups. Patients in group A were given methoxamine 10 mg i.m., 15 min before spinal anaesthesia.
CHAMBERS, F. A., CORCORAN, M. O., O'TOOLE, D. P., KEANE, P. W.   +3 more
core   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Spinal anaesthesia

, 2021
Spinal anaesthesia involves the injection of local anaesthetic solution into the intrathecal space. It is a widely practised anaesthetic technique that can provide surgical anaesthesia for procedures below the umbilicus.
Sadler, Amy L.K., Fettes, Paul D.W.
core   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Recovery after total intravenous general anaesthesia or spinal anaesthesia for total knee arthroplasty: a randomized trial. [Elektronisk resurs]

, 2013
BACKGROUND: /st>This study was undertaken to compare the effects of general anaesthesia (GA) and spinal anaesthesia (SA) on the need for postoperative hospitalization and early postoperative comfort in patients undergoing fast-track total knee ...
Toksvig-Larsen, Sören,, Harsten, Andreas,, Kehlet, H, Lund University.   +3 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Continuous Spinal Anaesthesia Versus Single-Shot Spinal Anaesthesia in Terms of Hemodynamic Stability

, 2022
A cross-sectional study was conducted based on observation and comparison, and this paper aimed to find out the effects of Continuous spinal anaesthesia versus single-shot spinal anaesthesia in terms of hemodynamic stability.
Dr. Layth Masood Saleh, Dr. Noor Alimardan Mohamad, Dr. Ayad Najm Abdulameer   +2 more
core   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source