Results 111 to 120 of about 530,815 (305)

Local versus Spinal Anesthesia for Endovenous Ablation Therapy: A Comparative Study

Cerrahpaşa Medical Journal
  Objective: Endovenous thermal ablation techniques such as endovenous laser ablation (EVLA) and radiofrequency ablation (RFA) are widely used in the treatment of chronic venous insufficiency.
Berk Arapi, Çiğdem Tel Üstünışık, Ozan Onur Balkanay, Elif Çiftçi, Nevzat Cem Sayılgan, Serkan Burç Deşer, Deniz Göksedef, Suat Nail Ömeroğlu, Gökhan İpek   +8 more
doaj   +1 more source

Comparison of general anesthesia with endotracheal intubation, combined spinal-epidural anesthesia, and general anesthesia with laryngeal mask airway and nerve block for intertrochanteric fracture surgeries in elderly patients: a retrospective cohort study

BMC Anesthesiology, 2019
Background There is no consensus on the optimal anesthesia method for intertrochanteric fracture surgeries in elderly patients. Our study aimed to compare the hemodynamics and perioperative outcomes of general anesthesia with endotracheal intubation ...
Yang Liu, Mang Su, Wei Li, Hao Yuan, Cheng Yang   +4 more
doaj   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Selected 2017 Highlights in Congenital Cardiac Anesthesia

, 2018
This article is a review of the highlights of pertinent literature published during the 12 months of 2017, which is of interest to the congenital cardiac anesthesiologist. Following a search of the US National Library of Medicine PubMed database, several
Walker, Scott G., Kussman, B. D., Nasr, V. G., Twite, M. D.   +3 more
core   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Total Spinal Anesthesia Failure

, 2017
Intrathecal local anesthetic maldistribution is a well-known cause of spinal anesthesia failure (SAF). This could potentially result in sensory blockade restricted to the sacral dermatomes. We sought to determine the overall incidence of SAF and the role
Andrew G. Day, Pinheiro Modolo, Norma Sueli [UNESP], Leandro Gobbo Braz, Leopoldo Muniz da Silva, Modolo, Marilia Pinheiro [UNESP], Ganem, Eliana Marisa [UNESP], Ronaldo Rodrigo de Sá Oliveira, Mizubuti, Glenio Bitencourt, Silva, Leopoldo Muniz da, Day, Andrew G., Norma Sueli Pinheiro Módolo, Guilherme Antonio Moreira de Barros, Eliana Marisa Ganem, Sa Oliveira, Ronaldo Rodrigo de [UNESP], Rachel Phelan, Ho, Anthony M. H., Anthony M. H. Ho, Navarro e Lima, Lais Helena [UNESP], Moreira de Barros, Guilherme Antonio [UNESP], Glênio Bitencourt Mizubuti, Lais Helena Navarro e Lima, Braz, Leandro Gobbo [UNESP], Marília Pinheiro Módolo, Phelan, Rachel   +23 more
core   +1 more source

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source

Correlative factors of post-dural puncture backache in cesarean section

فصلنامه دانشگاه علوم پزشکی جهرم, 2013
Introduction: Spinal anesthesia is an optional method chosen for cesarean section. One main reason for the decline of this method is backache. This study was conducted to investigate the factors associated with post-dural puncture backache in cesarean ...
Saeed Pasban Noghabi, Aarash Hamzei, Hossein Nazemi, Hossein Kamran Bilandy   +3 more
doaj  

Apprehension of paraplegia after undergoing spinal anesthesia in the central region population of Saudi Arabia: A cross-sectional study

Journal of Pharmacy and Bioallied Sciences
Aim: The aim of the present study was to determine the prevalence of paraplegia-related fear in spinal anesthesia among the general population in the central region of Saudi Arabia.
Faris Suleiman Saleh Aldobekhi, Manal M Almutairi, Mohammed H Alanazi, Badah M Aldawsari, Sarah S Almutairi, Abdulkarim K Alenazi, Abdulazizludba N Binmuhareb, Ghadi A Alfadhil, Shouq Y Alaoufi, Abdullah O Alqahtani   +9 more
doaj   +1 more source

Spinal cord ischemia following thoracotomy without epidural anesthesia

, 2006
Paraplegia is an uncommon yet devastating complication following thoracotomy, usually caused by compression or ischemia of the spinal cord. Ischemia without compression may be a result of global ischemia, vascular injury and other causes.
Saute, Milton, Raz, Aeyal, Avramovich, Aharon, Saraf-Lavi, Efrat, Eidelman, Leonid A   +4 more
core   +1 more source