Results 121 to 130 of about 104,778 (265)

T cells, the Next Big Target in Axial Spondyloarthritis?

open access: yesArthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Deep Immunophenotyping Reveals Distinct Immune Signatures in Axial Spondyloarthritis and Psoriatic Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are overlapping yet distinct conditions within the SpA spectrum. As divergent immunophenotypes may influence disease course and therapeutic response, we compared immune cell subsets, cytokine profiles, and inflammatory mediators.
Natalie Frede   +11 more
wiley   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease   +20 more
wiley   +1 more source

A Modified Arthroscopic Trans‐Septal Approach via the Figure‐to‐4 Position of the Knee

open access: yesArthroscopy Techniques, EarlyView.
Abstract Standard anterior and posterior portals offer limited access to pathologies in the posterior compartment of the knee. The trans‐septal portal facilitates comprehensive visualization and instrumentation in the posterolateral and posteromedial compartments.
Ning Sheng   +4 more
wiley   +1 more source

Prediction of spinal anesthesia-induced hypotension during cesarean delivery: a narrative review. [PDF]

open access: yesJ Anesth Analg Crit Care
Helmy MA   +7 more
europepmc   +1 more source

All‐Inside Arthroscopic Technique for Repairing Radial Meniscus Tears at the Anterior Horn–Body Junction

open access: yesArthroscopy Techniques, EarlyView.
Abstract Radial meniscus tears are a common tear pattern that, if left untreated, can ultimately lead to accelerated degenerative changes and disability. There is well‐established evidence that supports meniscal preservation in patients with radial meniscus tears.
Brandon Omari Boyd   +3 more
wiley   +1 more source

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