Results 121 to 130 of about 1,038,908 (406)

Mas-related G-protein–coupled receptors inhibit pathological pain in mice [PDF]

, 2010
An important objective of pain research is to identify novel drug targets for the treatment of pathological persistent pain states, such as inflammatory and neuropathic pain.
Altier, Baron, Basbaum, Cai, Calignano, Callaghan, Caterina, Chen, Chen, Coderre, Costigan, Costigan, D. J. Anderson, De Felipe, Delmas, Dong, Gerevich, Guan, Guan, Herrero, Honan, Ikeda, Julius, Knabl, Kusudo, Lembo, Li, Li, Liu, Liu, Lu, MacDermott, MacPherson, Malmberg, Melzack, Melzack, Miraucourt, Ndong, Neumann, Q. Liu, Rau, Rodriguez Parkitna, S. N. Raja, Scholz, Seal, Woolf, X. Dong, Y. Guan, Z. Tang, Zeng   +49 more
core   +2 more sources

Succinate Dehydrogenase Subunit A (SDHA) Mediated Microglia Extracellular Traps Formation Participating in Cerebral Ischemic Reperfusion Injury

Advanced Science, EarlyView.
This study investigates the mechanism of succinate dehydrogenase (SDH)‐mediated succinate oxidation in microglia extracellular traps (MiETs) formation and neuronal injury after cerebra I/R injury. Dimethyl malonate (DMM), a competitive SDH inhibitor, could reduce MiETosis by inhibiting succinate oxidation and mtROS production during reperfusion ...
Lili Zhao, Tao Li, Meijuan Dang, Ye Li, Jialiang Lu, Ziwei Lu, Zhiyang Chen, Qiao Huang, Yujie Chen, Yang Yang, Yuxuan Feng, Xiaoya Wang, Yating Jian, Heying Wang, Yingying Guo, Lei Zhang, Yu Jiang, Songhua Fan, Shengxi Wu, Hong Fan, Fang Kuang, Guilian Zhang   +21 more
wiley   +1 more source

Effect of Different Methods of Skin Infiltration of Local Anesthetics on Pain during Spinal Anesthesia Induction

مجله دانشکده پزشکی اصفهان, 2013
Background: Spinal anesthesia needs needle insertion through the skin into the subarachnoid space. In most patients, this insertion causes pain which leads to discomfort, stress, unintended moving and finally, failure in spinal block.
Sayed Jalal Hashemi, Gholam-Reza Khalili, Samanehsadat Moosavi   +2 more
doaj  

Prostatectomy — Spinal Anesthesia [PDF]

The Boston Medical and Surgical Journal, 1904
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openaire   +2 more sources

Spinal anesthesia; the Holy Grail?

Local and Regional Anesthesia, 2017
Marieke Voet, Cornelis SlagtDepartment of Anesthesiology, Pain and Palliative Care, Radboud University Medical Center, Nijmegen, The NetherlandsAfter reading the paper recently published in Local and Regional Anesthesia by Whitaker et al:1 “Spinal anesthesia after intraoperative cardiac arrest during general anesthesia in an infant,” we ...
Marieke Voet, Cornelis Slagt
openaire   +8 more sources

Calibrated forceps model of spinal cord compression injury. [PDF]

, 2015
Compression injuries of the murine spinal cord are valuable animal models for the study of spinal cord injury (SCI) and spinal regenerative therapy.
Ariza, Jeanelle, Martínez-Cerdeño, Verónica, McDonough, Ashley, Monterrubio, Angela   +3 more
core   +2 more sources

Choroid Plexus Fibroblast–ILC2 Niche Promotes Adult Hippocampal Neurogenesis after Traumatic Brain Injury

Advanced Science, EarlyView.
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao, Xiaoming Guo, Sixuan Tian, Huaping Huang, Caidi Ying, Junjie Wang, Jiahao Zhang, Jun Lin, Anwen Shao, Jingyu Wang, Yuan Hong   +10 more
wiley   +1 more source

CRITERIA OF ASSESSMENT OF HIGH SPINAL ANESTHESIA EFFICIENCY IN UPPER ABDOMEN SURGERIES

Acta Biomedica Scientifica, 2017
In recent years, the frequency of application of regional anesthesia methods, and especially in economically developed countries, has progressively increased.
A. B. Yakushevskiy, A. N. Plekhanov, A. V. Zharnikov   +2 more
doaj   +1 more source

Spinal Anesthesia in Pediatrics

, 2022
The survival of preterm newborn patients (PNB) depends in a great extent on the anesthetic technique used. Spinal anesthesia (SA) is considered the best-tolerated regional anesthetic method for highly unstable newborn infants (NB) with high risk of complications during the perioperative period.
Karen L. Iñiguez-Lopéz, Yolanda M. Martínez-Barragán, Enrique Hernández-Cortez   +2 more
openaire   +4 more sources

Spinal anesthesia increases the risk of venous thromboembolism in total arthroplasty

Medicine, 2017
Clinical guidance on the choice of anesthetic modality vis-à-vis the risk of perioperative venous thromboembolism (VTE) is largely lacking because of a paucity of recent evidence.
Mashio Nakamura, M. Kamei, S. Bito, K. Migita, S. Miyata, K. Kumagai, I. Abe, Y. Nakagawa, Y. Nakayama, M. Saito, Takaaki Tanaka, S. Motokawa   +11 more
semanticscholar   +1 more source