Results 121 to 130 of about 182,888 (311)

Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1‐Mediated Mechanotransduction

Advanced Science, EarlyView.
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park, Yurim Kim, Byeong Seong Jang, Simay Genişcan, Dong Hoon Hwang, Yeojin Seo, Seung‐Ah Jee, Hyo Gyeong Seo, Hyung Soon Kim, Ariandokht Einisadr, Ho‐Jeong Kim, Seolhee Lee, Sangwoo Kwon, Kyung Sook Kim, Kang In Lee, Jae Young Lee, Joo Min Park, Young‐Min Kim, Soo‐Chang Song, Byung Gon Kim   +19 more
wiley   +1 more source

Rapid Isolation of Dorsal Root Ganglion Macrophages. [PDF]

, 2019
There are growing interests to study the molecular and cellular interactions among immune cells and sensory neurons in the dorsal root ganglia after peripheral nerve injury.
Guan, Zhonghui, Leff, Jacqueline, Yu, Xiaobing   +2 more
core  

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Effect of Spinal Anesthesia versus General Anesthesia on Blood Glucose Concentration in Patients Undergoing Elective Cesarean Section Surgery: A Prospective Comparative Study [PDF]

, 2019
Khaled El-Radaideh, Ala”a Alhowary, Mohammad Alsawalmeh, Ahmed Abokmael, Haitham Odat, Amer Sindiani   +5 more
openalex   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

Advanced Science, EarlyView.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo, Yue Wang, Yong Ni, Bin Bo, Jinzhi He, Yongming Zhu, Aiping Qin, Xianyong Zhou, Huaping Du, Yuan Liu, Tianyao Wang, Yudu Li, Yibo Zhao, Zengai Chen, Zhipei Liang, Yao Li, Yuan Xu, Huiling Zhang   +17 more
wiley   +1 more source

Effect of Spinal Anesthesia on Blood Pressure During Cesarean Section in Private Indonesian Hospital

Majalah Kedokteran Bandung
The 2018 Indonesian Basic Health Research Data presented an increase in the number of cesarean sections from the previous years, with an increase of 17.6%.
Nassya Putri Nanmi, Husnul Lailly, Ita Armyanti, Poppy Novitarini, Willy Handoko   +4 more
doaj   +1 more source

Incidence and associated factors for hypotension after spinal anesthesia during cesarean section at Gandhi Memorial Hospital Addis Ababa, Ethiopia

, 2020
Bedru Jemal, Tewoderos Shitemaw, Temesgen Mamo, Leulayehu Akalu   +3 more
openalex   +1 more source

Continuous Spinal Anesthesia versus Combined Spinal Epidural Anesthesia for Major Orthopedic Hip Surgeries [PDF]

, 2020
Mohamed Saeed Abdelaziz, A N Elshaar, Ashraf Elsayed Elagamy, Mayada Ahmed Ibrahim, Mohamed Saleh   +4 more
openalex   +1 more source

Comparison of Ultrasound-Guided Caudal Epidural Blocks and Spinal Anesthesia for Anorectal Surgery: A Randomized Controlled Trial [PDF]

, 2022
Shibiao Chen, Aiping Wei, Min Jia, Lei Li, Yang Zhang   +4 more
openalex   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

Advanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu, Bixiao Liu, Yu Yang, Tao Meng, Yuanyuan Chang, Yao Peng, Jia Guo, Zhuqing Wang, Hongqian Guo, Liuhua Zhou, Xiaozhi Zhao   +10 more
wiley   +1 more source