Results 71 to 80 of about 103,063 (318)

The impact of height on the spread of spinal anesthesia and stress response in parturients undergoing caesarean section: a prospective observational study

open access: yesBMC Anesthesiology, 2021
Background The spread of spinal anesthesia was influenced by many factors, and the effect of body height on spinal anesthesia is still arguable. This study aimed to explore the impact of height on the spread of spinal anesthesia and the stress response ...
Ying-Jun She   +5 more
doaj   +1 more source

Noninvasive Blockade of Action Potential by Electromagnetic Induction [PDF]

open access: yesarXiv, 2018
Conventional anesthesia methods such as injective anesthetic agents may cause various side effects such as injuries, allergies, and infections. We aim to investigate a noninvasive scheme of an electromagnetic radiator system to block action potential (AP) in neuron fibers.
arxiv  

Conjugacy classes of polyspinal groups [PDF]

open access: yesarXiv, 2022
Spinal groups and multi-GGS groups are both generalisations of the well-known Grigorchuk-Gupta-Sidki (GGS-)groups. Here we give a necessary condition for spinal groups to be conjugate, and we establish a necessary and sufficient condition for multi-GGS groups to be conjugate.
arxiv  

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

open access: yesAdvanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li   +12 more
wiley   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

An Adaptive Neuro-fuzzy Strategy in Closed-loop Control of Anesthesia [PDF]

open access: yesarXiv, 2019
This paper proposes an adaptive neuro-fuzzy framework to improve drug infusion rate in closed-loop control of anesthesia. The proposed controller provides a sub-optimal propofol administration rate as input to reach the desired bispectral index, which is the output of the system, in both induction and maintenance phases.
arxiv  

Low‐Irradiance Antimicrobial Blue Light‐Bathing Therapy for Wound Infection Control

open access: yesAdvanced Science, EarlyView.
Antimicrobial blue light has been shown as an appealing non‐pharmacological antimicrobial alternative. However, its clinical applications have been hindered by high irradiance‐associated photothermal risks. In this work, a low‐irradiance blue light‐bathing concept and a wearable photonic wound patch are established to address this challenge in terms of
Jie Hui   +12 more
wiley   +1 more source

Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]

open access: yesarXiv, 2022
Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv  

A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis

open access: yesAdvanced Science, EarlyView.
The dynamic interplay between central respiratory chemoreceptors and the respiratory central pattern generator is essential for maintaining stable respiratory rhythm and patterns, particularly during sleep. This study offers novel insights into the anatomical, molecular, and functional characteristics of a medullary network involving the nucleus ...
Tianjiao Deng   +16 more
wiley   +1 more source

UGDH Lactylation Aggravates Osteoarthritis by Suppressing Glycosaminoglycan Synthesis and Orchestrating Nucleocytoplasmic Transport to Activate MAPK Signaling

open access: yesAdvanced Science, EarlyView.
Lactylation of UDP‐glucose dehydrogenase (UGDH) represses its enzymatic activity and causes glycosaminoglycans loss. In addition, UGDH lactylation facilitates its interaction with chromosome region maintenance 1 (CRM1) and promotes the nucleocytoplasmic transport.
Weiren Lan   +8 more
wiley   +1 more source

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