Results 71 to 80 of about 174,410 (337)

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source

The impact of height on the spread of spinal anesthesia and stress response in parturients undergoing caesarean section: a prospective observational study

BMC Anesthesiology, 2021
Background The spread of spinal anesthesia was influenced by many factors, and the effect of body height on spinal anesthesia is still arguable. This study aimed to explore the impact of height on the spread of spinal anesthesia and the stress response ...
Ying-Jun She, Wen-Xing Liu, Ling-Yu Wang, Xin-Xu Ou, Hui-Hong Liang, Dong-Xu Lei   +5 more
doaj   +1 more source

Global Burden Related to Nitrous Oxide Exposure in Medical and Recreational Settings: A Systematic Review and Individual Patient Data Meta-Analysis. [PDF]

, 2019
The risk of adverse effects of nitrous oxide (N2O) exposure is insufficiently recognized despite its widespread use. These effects are mainly reported through case reports. We conducted an individual patient data meta-analysis to assess the prevalence of
Filhine-Tresarrieu, Pierre, Franczak, Claire, Green, Ralph, Guéant, Jean-Louis, Hajjar, Olivia, Julien, Mélissa, Laugel, Elodie, Levy, Julien, Oussalah, Abderrahim, Stephan, Charlotte, Wandzel, Marion   +10 more
core   +3 more sources

Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model

Advanced Science, EarlyView.
A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana, Ryan Sentosa, Caterina Sturtzel, Martin Pfister, René Werkmeister, Anna Schmitt, David Traver, Rainer Leitgeb, Wolfgang Drexler, Martin Distel, Angelika Unterhuber   +10 more
wiley   +1 more source

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

Anatomy of Soft Tissues of the Spinal Canal [PDF]

, 1999
Background and Objectives. Important issues regarding the spread of solutions in the epidural space and the anatomy of the site of action of spinal and epidural injections are unresolved.
Quinn, Hogan, Toth, Jeffrey M.
core   +1 more source

Postoperative delirium after major orthopedic surgery. [PDF]

, 2020
BACKGROUND: Postoperative delirium (POD) is one of the most common complications in older adult patients undergoing elective surgery. Few studies have compared, within the same institution, the type of surgery, risk factors and type of anesthesia and ...
Magid, Steven K., Sasaki, Mayu, Schmucker, Abigail M., Urban, Michael K.   +3 more
core   +1 more source

Choroid Plexus Fibroblast–ILC2 Niche Promotes Adult Hippocampal Neurogenesis after Traumatic Brain Injury

Advanced Science, EarlyView.
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao, Xiaoming Guo, Sixuan Tian, Huaping Huang, Caidi Ying, Junjie Wang, Jiahao Zhang, Jun Lin, Anwen Shao, Jingyu Wang, Yuan Hong   +10 more
wiley   +1 more source

General versus Spinal Anesthesia: Comparison of Complications and Outcomes in Lumbar Laminectomy Surgery [PDF]

Background: This study was designed to compare the complications and outcomes of lumbar laminectomy surgery performed by general and spinal anesthesia.
Hosein Taravati, Associate Professor, Department of Anesthesiology, Afzalipour Sc, Mohsen Shahba, Assistant Professor, Department of Neurosurgery , Afzalipour Sch, Reza Javdani, Resident, Department of Neurosurgery, Afzalipour School of Medic   +2 more
core  

Benefits of using intrathecal buprenorphine [PDF]

, 2014
Background: General anesthesia draws attention to the most commonly used modalities for post cesarean delivery pain relief in systemic administration of opioids, while the administration of small dose of intrathecal opioid during spinal anesthesia can be
Alijanpour, E., Jabbari, A., Rabiee, S.M., Rostami, S.   +3 more
core