Results 101 to 110 of about 743,476 (308)

Impaired transmission in the corticospinal tract and gait disability in spinal cord injured persons [PDF]

, 2010
Rehabilitation following spinal cord injury is likely to depend on recovery of corticospinal systems. Here we investigate whether transmission in the corticospinal tract may explain foot drop (inability to dorsiflex ankle) in persons with spinal cord ...
Barthélemy, Dorothy, Barthélemy, Dorothy, Biering-Sørensen, Fin, Biering-Sørensen, Fin, Conway, Bernard A, Conway, Bernard A., Holm-Nielsen, Jens Bo, Knudsen, Hanne, Knudsen, Hanne, Lundell, Hans Magnus Henrik, Lundell, Henrik, Nielsen, Jens Bo, Willerslev-Olsen, Maria, Willerslev-Olsen, Maria   +13 more
core   +1 more source

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Combined cerebellar and bilateral cervical posterior spinal artery stroke demonstrated on MRI [PDF]

, 2003
Combined cerebellar and spinal ischemic stroke is a rare, critical condition. We report a patient with combined cerebellar and bilateral posterolateral cervical spinal cord infarction due to bilateral stenosis of the vertebral arteries. MRI is the method
Brückmann, H., Hamann, Gerhard F., Liebetrau, M., Müller-Schunk, S., Reich, P., Scheuerer, W.   +5 more
core   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Engagement of People With Lived Experience in Spinal Cord Injury to Address Innovation Priorities

Health Expectations
Introduction The involvement of people with lived experience (PLEX) of spinal cord injury (SCI) is not common during medical innovation design, research and commercialization processes.
Julia T. Ross, Vanessa K. Noonan, John Chernesky, James Hektner, Richard Peter, Spring Hawes, Andrew Forshner, Shweta Shekhar, Tathagata Ray, Arushi Raina, James J. Laskin   +10 more
doaj   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Optimizing transcutaneous spinal stimulation: excitability of evoked spinal reflexes is dependent on electrode montage

Journal of NeuroEngineering and Rehabilitation
Background There is growing interest in use of transcutaneous spinal stimulation (TSS) for people with neurologic conditions both to augment volitional control (by facilitating motoneuron excitability), and to decrease spasticity (by activating ...
Kelly Lynn Thatcher, Karen Emily Nielsen, Evan Blake Sandler, Oliver John Daliet, Jennifer Ann Iddings, Edelle Carmen Field-Fote   +5 more
doaj   +1 more source

Intradural angiomatous meningioma arising from a thoracic nerve root [PDF]

, 2017
BACKGROUND: Spinal intradural meningiomas that arise purely from a nerve root without dural attachments are extremely rare. Spinal meningiomas arise from arachnoidal cap cells in the spinal canal, and growth of these tumors exerts pressure on the spinal ...
Domenicucci, Maurizio, Grazia Elefante, Maria, Missori, Paolo, Palmarini, Valeria, Paolini, Sergio, Scapeccia, Marco   +5 more
core   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Triple leads with longitudinal guarded cathodes in spinal cord stimulation-effect of transversal lead separation [PDF]

, 2009
In spinal cord stimulation (SCS) clinical practice, longitudinal guarded cathode stimulation by a single lead, placed on the spinal cord midline provides the broadest parasthesia coverage.
Buitenweg, J.R., Holsheimer, J., Sankarasubramanian, V   +2 more
core   +1 more source