Results 151 to 160 of about 531,097 (305)
24p3R is an astrocytic receptor for α‐Syn uptake. When LCN2 is secreted from astrocytes, it binds to its receptor 24p3R in astrocytes and this binding impedes the α‐Syn PFF binding to 24p3R. This in turn inhibits 24p3R‐mediated α‐Syn PFF uptake and reduces the clearance of extracellular α‐Syn by astrocytes, which contributes to α‐Syn spread and ...
Ying‐Ying Jiao +14 more
wiley +1 more source
Quantification of Lower Limb Kinematics During Swimming in Individuals with Spinal Cord Injury
Spinal cord injuries (SCI) often result in impaired motor functions. To quantify these impairments, swimming patterns were analyzed in individuals with SCI.
Melina Giagiozis +5 more
doaj +1 more source
VI. On the changes in movement and sensation produced by hemisection of the spinal cord in the cat [PDF]
Charles Devereux Marshall
openalex +1 more source
Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang +16 more
wiley +1 more source
SOME MORPHOLOGICAL FEATURES OF THE SPINAL CORD IN THE RABBIT, WITH SPECIAL REFERENCE TO THE PRODUCTION OF ARTIFACTS [PDF]
O. A. Trowell
openalex +1 more source
Modulation of Radiation – Induced tumor necrosis factor α (TNF-α) Gene Expression in the Rats Spinal Cord by Melatonin [PDF]
The spinal cord is the major dose- limiting organ for radiotherapy of cancer in the head and neck region. Understanding the cellular and molecular mechanisms may help to develop strategies to either increase the radiation tolerance or to treat spinal ...
حدادی, غلامحسن +4 more
core
Capsaicin enhances lipid metabolism, reduces lipid deposition, and alleviates AD‐related pathologies. Capsaicin activates PPARA, promoting the expression of PPAR signaling pathway‐related genes and accelerating lipid metabolism. Capsaicin upregulates ATP6V0E1‐V‐ATPase‐mediated lysosomal acidification, enhancing lipid droplet clearance. PPARA is the key
Haitao Yu +12 more
wiley +1 more source
Pyogenic infective Diseases of the Brain Spinal Cord; Meningitis; Abscess Brain; Infective Sinus Thrombosis. By Macewen William, M. D. Glasgow: James Maclehose and Sons. 1893. [PDF]
D. Norman Grant
openalex +1 more source
Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao +9 more
wiley +1 more source

