Results 51 to 60 of about 864,972 (305)

Accuracy and Safety of Pedicle Screw Insertion Using Novel Intraoperative Computed Tomography Navigation System for Spinal Fusion Surgery

Spine Surgery and Related Research
Introduction: Accurate pedicle screw placement is critical in spinal fusion surgery to prevent complications such as neurological and vascular injuries.
Atsushi Kojima, Shuhei Iwata, Shigeru Kamitani, Naoki Tsujishima, Hirohito Suzuki, Tomonori Sodeyama, Seiji Ohtori, Kenji Hatakeyama   +7 more
doaj   +1 more source

Minimum toe clearance: probing the neural control of locomotion

Scientific Reports, 2017
Minimum toe clearance (MTC) occurs during a highly dynamic phase of the gait cycle and is associated with the highest risk of unintentional contact with obstacles or the ground. Age, cognitive function, attention and visual feedback affect foot clearance
Tim Killeen, Christopher S. Easthope, László Demkó, Linard Filli, Lilla Lőrincz, Michael Linnebank, Armin Curt, Björn Zörner, Marc Bolliger   +8 more
doaj   +1 more source

Investigation of perfusion impairment in degenerative cervical myelopathy beyond the site of cord compression

Scientific Reports, 2023
The aim of this study was to determine tissue-specific blood perfusion impairment of the cervical cord above the compression site in patients with degenerative cervical myelopathy (DCM) using intravoxel incoherent motion (IVIM) imaging.
Anna Lebret, Simon Lévy, Nikolai Pfender, Mazda Farshad, Franziska C. S. Altorfer, Virginie Callot, Armin Curt, Patrick Freund, Maryam Seif   +8 more
doaj   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Microdialysis to optimize cord perfusion and drug delivery in spinal cord injury. [PDF]

, 2016
OBJECTIVE: There is lack of monitoring from the injury site to guide management of patients with acute traumatic spinal cord injury. Here we describe a bedside microdialysis monitoring technique for optimizing spinal cord perfusion and drug delivery at ...
Abrahamsson, Abrahamsson, Balis, Bernards, Bracken, Bracken, Carpenter, Casha, Dahyot-Fizelier, Fehlings, Fehlings, Frasca, Hutchinson, Hutchinson, Inoue, Kitagawa, Kobayakawa, Lee, Okon, Papadopoulos, Phang, Phang, Phang, Phang, Plock, Quan, Saadoun, Saadoun, Shannon, Timofeev, Vandenabeele, Varsos, Walters, Werndle, Werndle, Werndle   +35 more
core   +1 more source

Neurophysiological markers predicting recovery of standing in humans with chronic motor complete spinal cord injury

Scientific Reports, 2019
The appropriate selection of individual-specific spinal cord epidural stimulation (scES) parameters is crucial to re-enable independent standing with self-assistance for balance in individuals with chronic, motor complete spinal cord injury, which is a ...
Samineh Mesbah, Federica Gonnelli, Claudia A. Angeli, Ayman El-baz, Susan J. Harkema, Enrico Rejc   +5 more
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Analysis of current density and related parameters in spinal cord stimulation [PDF]

, 1998
A volume conductor model of the spinal cord and surrounding anatomical structures is used to calculate current (and current density) charge per pulse, and maximum charge density per pulse at the contact surface of the electrode in the dorsal epidural ...
Boom, Herman B.K., Holsheimer, Jan, Wesselink, Wilbert A.   +2 more
core   +3 more sources

Feasibility of visual instrumented movement feedback therapy in individuals with motor incomplete spinal cord injury walking on a treadmill

Frontiers in Human Neuroscience, 2014
Background: Incomplete spinal cord injury (iSCI) leads to motor and sensory deficits. Even in ambulatory persons with good motor function an impaired proprioception may result in an insecure gait.
Daniel eSchließmann, Christian eSchuld, Matthias eSchneiders, Steffen eDerlien, Maria eGlöckner, Till eGladow, Norbert eWeidner, Rüdiger eRupp   +7 more
doaj   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
wiley   +1 more source