Results 71 to 80 of about 487,231 (316)

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Clinical outcomes of unpowered osteotome-assisted unilateral biportal endoscopy (UBE) for the treatment of lumbar spinal stenosis: a retrospective cohort study

European Journal of Medical Research
Study design Retrospective cohort study. Objective To compare the clinical and radiographic outcomes of unpowered osteotome-assisted versus powered drill-assisted unilateral biportal endoscopy (UBE) for the treatment of single-level lumbar spinal ...
Weiran Hu, Hongqiang Wang, Haoxu Wang, Chuang Wang, Xinge Shi, Yanzheng Gao, Kai Zhang   +6 more
doaj   +1 more source

Beyond treatment of chronic pain: a scoping review about epidural electrical spinal cord stimulation to restore sensorimotor and autonomic function after spinal cord injury

Neurological Research and Practice, 2023
Epidural electrical epinal cord stimulation (ESCS) is an established therapeutic option in various chronic pain conditions. In the last decade, proof-of-concept studies have demonstrated that ESCS in combination with task-oriented rehabilitative ...
Antonia Luz, Rüdiger Rupp, Rezvan Ahmadi, Norbert Weidner   +3 more
doaj   +1 more source

Double dural spinal sheath:a cadaveric case report [PDF]

, 2010
A previously unreported variation in the anatomy of the spinal dural sheath was observed during routine cadaveric dissection, consisting of a duplication of the dural layer, with layers adherent throughout their length. The double dural sheath completely
Loughenbury, Peter, Soames, Roger, Wadhwani, Sharan   +2 more
core  

Primitive roles for inhibitory interneurons in developing frog spinal cord [PDF]

, 2004
Understanding the neuronal networks in the mammal spinal cord is hampered by the diversity of neurons and their connections. The simpler networks in developing lower vertebrates may offer insights into basic organization.
Parry, D.M., Parry, DM, Higashijima, S., Roberts, A, Higashijima, S-I, Li, Wenchang, Soffe, S.R., Soffe, SR, Li, W-C   +8 more
core   +1 more source

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Chronic thoracic hemisection spinal cord injury in adult rats induces a progressive decline in transmission from uninjured fibers to lumbar motoneurons

, 2008
Although most spinal cord injuries are anatomically incomplete, only limited functional recovery has been observed in people and rats with partial lesions.
Hunanyan, Arsen, John K. Robinson, Schnell, Lisa, Golshani, Roobeh, Li Lou, Roobeh Golshani, Lou, Li, Robinson, John, Lisa Schnell, Ghosh, Arko, Victor L. Arvanian, Schwab, Martin, Damien D. Pearse, Arvanian, Victor, Arsen Hunanyan, Martin E. Schwab, Arko Ghosh, Mendell, Lorne, James W. Fawcett, Lorne M. Mendell, Pearse, Damien, Fawcett, James   +21 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

The Case of a 55‐Year‐Old Man With Leg Weakness

Annals of Clinical and Translational Neurology, EarlyView.
Ada Breitenbucher, Connor Welsh, Kelly Braun, Michael V. Robers   +3 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source