Results 71 to 80 of about 1,533,125 (359)

Neurotropin exerts neuroprotective effects after spinal cord injury by inhibiting apoptosis and modulating cytokines

Journal of Orthopaedic Translation, 2021
Background/objective: Spinal cord injury (SCI) severely and irreversibly damages the central nervous system. Neurotropin (NTP), a nonprotein extract obtained from inflamed rabbit skin inoculated with vaccinia virus, is a drug that has been used for more ...
Xue Yao, Chao Sun, Baoyou Fan, Chenxi Zhao, Yan Zhang, Huiquan Duan, Yilin Pang, Wenyuan Shen, Bo Li, Xu Wang, Chang Liu, Hengxing Zhou, Xiaohong Kong, Shiqing Feng   +13 more
doaj  

Alternating current stimulation promotes neurite outgrowth and plasticity in neurons through activation of the PI3K/AKT signaling pathway

Acta Biochimica et Biophysica Sinica, 2023
As a commonly used physical intervention, electrical stimulation (ES) has been demonstrated to be effective in the treatment of central nervous system disorders.
Zhong Hao, Xing Cong, Zhou Mi, Jia Zeyu, Liu Song, Zhu Shibo, Li Bo, Yang Hongjiang, Ma Hongpeng, Wang Liyue, Zhu Rusen, Qu Zhigang, Ning Guangzhi   +12 more
doaj   +1 more source

Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury.

ACS Nano, 2019
Individuals with spinal cord injury (SCI) usually suffer from permanent neurological deficits, while spontaneous recovery and therapeutic efficacy are limited.
Shaowei Guo, Nisim Perets, O. Betzer, S. Ben-Shaul, A. Sheinin, I. Michaelevski, R. Popovtzer, D. Offen, S. Levenberg   +8 more
semanticscholar   +1 more source

Surface dose analysis and dosimetric comparison of Halcyon versus Truebeam in breast cancer radiotherapy: An OSL dosimetry study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Breast cancer is a neoplastic disease with high prevalence among women. Radiotherapy is one of the principal treatment modalities for this disease, but it poses significant challenges. This study aimed to compare and evaluate the technical and dosimetric performance of conventional C‐arm linac systems and a new design, Halcyon, in the ...
Mustafa Çağlar, Kudret Akçay, Esra Serin, Dursun Eşitmez, Mehmet Sıddık Cebe, Navid Kheradmand, Ömer Yazıcı, Dilek Ünal, Evrim Metcalfe   +8 more
wiley   +1 more source

Mediolateral damping of an overhead body weight support system assists stability during treadmill walking

Journal of NeuroEngineering and Rehabilitation, 2020
Background Body weight support systems with three or more degrees of freedom (3-DoF) are permissive and safe environments that provide unloading and allow unrestricted movement in any direction.
M. Bannwart, S. L. Bayer, N. König Ignasiak, M. Bolliger, G. Rauter, C. A. Easthope   +5 more
doaj   +1 more source

Regulation of peripheral inflammation by spinal p38 MAP kinase in rats. [PDF]

, 2006
BackgroundSomatic afferent input to the spinal cord from a peripheral inflammatory site can modulate the peripheral response. However, the intracellular signaling mechanisms in the spinal cord that regulate this linkage have not been defined.
Albani, Salvatore, Boyle, David L, Firestein, Gary S, Hammaker, Deepa, Jones, Toni L, Rosengren, Sanna, Sorkin, Linda, Svensson, Camille I   +7 more
core   +3 more sources

Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis

Brain : a journal of neurology, 2018
Neuro-axonal injury is a key factor in the development of permanent disability in multiple sclerosis. Neurofilament light chain in peripheral blood has recently emerged as a biofluid marker reflecting neuro-axonal damage in this disease.
Christian Barro, P. Benkert, G. Disanto, C. Tsagkas, M. Amann, Y. Naegelin, D. Leppert, C. Gobbi, C. Granziera, Ö. Yaldizli, Z. Michalak, J. Wuerfel, L. Kappos, K. Parmar, J. Kuhle   +14 more
semanticscholar   +1 more source

An extension to the OVH concept for knowledge‐based dose volume histogram prediction in lung tumor volumetric‐modulated arc therapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Volumetric‐modulated arc therapy (VMAT) treatment planning allows a compromise between a sufficient coverage of the planning target volume (PTV) and a simultaneous sparing of organs‐at‐risk (OARs). Particularly in the case of lung tumors, deciding whether it is possible or worth spending more time on further improvements of a treatment
Johann Brand, Juliane Szkitsak, Oliver J. Ott, Christoph Bert, Stefan Speer   +4 more
wiley   +1 more source

Feasibility of visual instrumented movement feedback therapy in individuals with motor incomplete spinal cord injury walking on a treadmill

Frontiers in Human Neuroscience, 2014
Background: Incomplete spinal cord injury (iSCI) leads to motor and sensory deficits. Even in ambulatory persons with good motor function an impaired proprioception may result in an insecure gait.
Daniel eSchließmann, Christian eSchuld, Matthias eSchneiders, Steffen eDerlien, Maria eGlöckner, Till eGladow, Norbert eWeidner, Rüdiger eRupp   +7 more
doaj   +1 more source

Beyond treatment of chronic pain: a scoping review about epidural electrical spinal cord stimulation to restore sensorimotor and autonomic function after spinal cord injury

Neurological Research and Practice, 2023
Epidural electrical epinal cord stimulation (ESCS) is an established therapeutic option in various chronic pain conditions. In the last decade, proof-of-concept studies have demonstrated that ESCS in combination with task-oriented rehabilitative ...
Antonia Luz, Rüdiger Rupp, Rezvan Ahmadi, Norbert Weidner   +3 more
doaj   +1 more source