Results 181 to 190 of about 416,929 (394)

Deferasirox Derivatives as Inhibitors of Kallikrein‐Related Peptidases Associated to Neurodegenerative Diseases

open access: yesChemMedChem, EarlyView.
Dysregulated proteolysis mediated by kallikrein‐related peptidases (KLKs) and iron overload are involved in the progression of neurodegenerative diseases. Deferasirox, an clinically‐approved iron chelator, and its newly synthesized derivatives have been identified as inhibitors of major central nervous system KLKs with low cytotoxicity and effective ...
Rilès Boumali   +11 more
wiley   +1 more source

Skeletal Muscle Memory: An Update From the Antidoping Perspective

open access: yesDrug Testing and Analysis, EarlyView.
ABSTRACT This narrative review explores the concept of muscle memory, focusing on the physiological and biochemical mechanisms underlying information retention in skeletal muscle tissue as it relates to antidoping. The discussion encompasses the role of satellite cells (SCs) in myonuclei recruitment, resulting in increased myonuclear density and ...
Claire Traversa
wiley   +1 more source

Transcatheter arterial embolization for relapsed spinal metastatic paraganglioma: A case report

open access: yesRadiology Case Reports, 2019
Spinal metastasis is a rare presentation of paraganglioma and an effective therapy for nonresectable spinal metastatic paraganglioma (MPG) has not yet been established.
Wataru Makino, MD   +4 more
doaj  

Dynamic MRI to Diagnose Spinal Canal Stenosis not Visualized on Standard Static MRI in patients with Cervical Spondylotic Myelopathy [PDF]

open access: yes
Background: Cervical Spondylotic Myelopathy (CSM) is a common disease of the cervical spine that affects people during and after middle age. To date, imaging preformed preoperatively consists of MRI of the cervical spine in neutral position.
Engelhard, Gabrielle L
core   +1 more source

What else is new in Cancer care? Breathlessness in lung cancer patients. Telephone interview included in article by Jane Hobden in Frontline 3rd August 2005 [PDF]

open access: yes, 2005
Telephone interview with Caroline Belchamber, a Senior 1 Physiotherapist at Poole ...
Belchamber, C.A., Hobden, Jane
core  

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng   +2 more
wiley   +1 more source

Nanowire‐Based Flexible Sensors for Wearable Electronics, Brain–Computer Interfaces, and Artificial Skins

open access: yesElectron, EarlyView.
The review systematically examines the potential of nanowires in flexible sensing technologies, addressing their application in wearable electronics, brain–computer interfaces, and electronic skins. It covers the fundamental understanding of nanowire properties, key design principles for high‐performance flexible sensors, and the challenges encountered
Xiaopan Song   +4 more
wiley   +1 more source

Grasp Force Assistance via Throttle-based Wrist Angle Control on a Robotic Hand Orthosis for C6-C7 Spinal Cord Injury [PDF]

open access: yesarXiv
Individuals with hand paralysis resulting from C6-C7 spinal cord injuries frequently rely on tenodesis for grasping. However, tenodesis generates limited grasping force and demands constant exertion to maintain a grasp, leading to fatigue and sometimes pain.
arxiv  

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