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Current Treatment Options in Neurology, 2012
Malignant epidural spinal cord compression (MESCC) remains a common neuro-oncologic emergency with high associated morbidity. Despite widespread availability of MRI, the diagnosis frequently goes unmade until myelopathy supervenes, which is unfortunate because the strongest predictor of neurologic outcome with treatment is the neurologic status when ...
David Schiff, Eduardo Carvalhal Ribas
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Malignant epidural spinal cord compression (MESCC) remains a common neuro-oncologic emergency with high associated morbidity. Despite widespread availability of MRI, the diagnosis frequently goes unmade until myelopathy supervenes, which is unfortunate because the strongest predictor of neurologic outcome with treatment is the neurologic status when ...
David Schiff, Eduardo Carvalhal Ribas
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Malignant spinal-cord compression
The Lancet Oncology, 2005Malignant spinal-cord compression (MSCC) is a common complication of cancer and has a substantial negative effect on quality of life and survival. Despite widespread availability of good diagnostic technology, studies indicate that most patients are diagnosed only after they become unable to walk.
David Schiff, Dheerendra Prasad
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Epidural spinal cord compression
Critical Reviews in Oncology/Hematology, 2005Spinal cord compression from epidural metastases (epidural spinal cord compression, ESCC) is the most common neurological complication of cancer after brain metastases. Extradural compression represents 97% of spinal cord metastatic lesions. ESCC usually occurs in patients with disseminated disease. The most common tumours associated with ESCC are lung
Spinazzé S, Caraceni A, Schrijvers D
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Neurologic Clinics, 2003
Back pain and suspected spinal cord compression remains one of the most frequent reasons for neurologic consultation in cancer patients. While treatment generally results in stabilization or improvement, early diagnosis remains the cornerstone of improving neurologic outcome.
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Back pain and suspected spinal cord compression remains one of the most frequent reasons for neurologic consultation in cancer patients. While treatment generally results in stabilization or improvement, early diagnosis remains the cornerstone of improving neurologic outcome.
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Metastatic spinal cord compression
BMJ, 2011Metastatic spinal cord compression is defined radiographically as an epidural metastatic lesion causing true displacement of the spinal cord from its normal position in the spinal canal.1 It is an important source of morbidity (including paralysis and bowel and bladder disorders) in patients with systemic cancer.
Claire Esler, Nasir A. Quraishi
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Methylprednisolone in Spinal Cord Compression
Spine, 1989In acute nonsurvival studies, eight anesthetized lambs were subjected to cord compression at T13 by means of an epidural balloon distended to a pressure of 200 mm Hg for 40 minutes. Subsequent to withdrawal of the balloon, each animal received 30 mg/kg of methylprednisolone succinate in an intravenous bolus followed by a continuous infusion of 10 mg/kg/
T Hansen+5 more
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2016
Spinal cord compression refers to an inward displacement of the dural sac and/or its contents by a lesion arising outside of the spinal cord. It is caused by metastatic or primary spine tumors, disk herniations, vertebral fractures, cysts, spinal epidural abscesses and hematomas, and degenerative disease most commonly.
Florencia Álamos, Ana Lorena Abello
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Spinal cord compression refers to an inward displacement of the dural sac and/or its contents by a lesion arising outside of the spinal cord. It is caused by metastatic or primary spine tumors, disk herniations, vertebral fractures, cysts, spinal epidural abscesses and hematomas, and degenerative disease most commonly.
Florencia Álamos, Ana Lorena Abello
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2021
Malignant spinal cord compression is a dreaded consequence of advanced cancer. Patients with this condition have an average life expectancy of 3–6 months. Diagnosis is dependent upon a high index of suspicion, thorough physical exam, and advanced imaging. A multidisciplinary approach to treatment is required to ensure optimal outcomes.
Jayne Viets-Upchurch+1 more
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Malignant spinal cord compression is a dreaded consequence of advanced cancer. Patients with this condition have an average life expectancy of 3–6 months. Diagnosis is dependent upon a high index of suspicion, thorough physical exam, and advanced imaging. A multidisciplinary approach to treatment is required to ensure optimal outcomes.
Jayne Viets-Upchurch+1 more
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Metastatic spinal cord compression
British Journal of Hospital Medicine, 2020Metastatic spinal cord compression is compression of the spinal cord or cauda equina as a result of metastatic deposits in the spinal column. It affects approximately 4000 cases per year in England and Wales. Prompt identification and treatment of metastatic spinal cord compression is necessary to prevent irreversible neurological injury, treat pain ...
Praveen Inaparthy+3 more
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Spinal cord compression in pseudohypoparathyroidism
The Spine Journal, 2013Spinal cord compression associated with pseudohypoparathyroidism (PHP) is an increasingly reported sequelae of the underlying metabolic syndrome. The association of neurologic dysfunction with PHP is not well appreciated. We believe this to be secondary to a combination of underlying congenital stenosis, manifest by short pedicles secondary to ...
Dean N Papaliodis+4 more
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