Results 71 to 80 of about 416,929 (394)

Contemporary treatment with radiosurgery for spine metastasis and spinal cord compression in 2015

open access: yesRadiation Oncology Journal, 2015
With the progress of image-guided localization, body immobilization system, and computerized delivery of intensity-modulated radiation delivery, it became possible to perform spine radiosurgery.
S. Ryu   +5 more
semanticscholar   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Clinical and magnetic resonance imaging characteristics of thoracolumbar intervertenral disk extrusions and protrusions in large breed dogs [PDF]

open access: yes, 2002
It has recently been shown that the fat-derived hormone adiponectin has the ability to decrease hyperglycemia and to reverse insulin resistance. However, bacterially produced full-length adiponectin is functionally inactive. Here, we show that endogenous
Beltran, E   +5 more
core   +4 more sources

The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury

open access: yesNeural Regeneration Research, 2023
Chronic compressive spinal cord injury in compressive cervical myelopathy conditions can lead to rapid neurological deterioration in the early phase, followed by partial self-recovery, and ultimately an equilibrium state of neurological dysfunction ...
Zhengran Yu   +4 more
doaj   +1 more source

Assessment of Cerebrospinal Fluid Pressure Dynamics in Patients with Degenerative Cervical Myelopathy [PDF]

open access: yes
With aging societies, chronic spinal cord compression such as degenerative cervical myelopathy (DCM) is becoming an increasingly prevalent condition. In DCM, a collection of age-related pathologies leads to the narrowing of the cervical spinal canal and ...
Kheram, Najmeh
core   +1 more source

Malignant Spinal Cord Compression

open access: yesJournal of the Royal College of Physicians of Edinburgh, 2019
Malignant spinal cord compression (MSCC) is a potentially devastating consequence of cancer. Early recognition of the signs and symptoms of MSCC can allow diagnosis prior to the development of irreversible complications. Information provision to patients and doctors regarding the risk of MSCC and a streamlined pathway for further investigation are ...
A. Graham Macdonald   +3 more
openaire   +2 more sources

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

Are surgical outcomes for one level anterior decompression and fusion associated with MRI parameters for degenerative cervical myelopathy?

open access: yesFrontiers in Surgery, 2022
BackgroundOur study is to determine the correlation between preoperative MRI parameters of spinal cord compression and the effects of anterior surgery in patients with degenerative cervical myelopathy (DCM).Methods24 normal subjects with no evident ...
Luqiang Qu   +8 more
doaj   +1 more source

Engineered Chitosan‐Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer   +10 more
wiley   +1 more source

The role of radiation therapy in bone metastases management [PDF]

open access: yes, 2017
Bone metastases represent an important complication of malignant tumours. Despite improvement in surgical techniques and advances in systemic therapies, management of patients with bone metastatic disease remains a powerful cornerstone for the radiation ...
DE FELICE, Francesca   +3 more
core   +1 more source

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