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Potential applications of focused ultrasound for spinal cord diseases: a narrative review of preclinical studies [PDF]

open access: yesBrain and Spine
Focused ultrasound (FUS) technology provides unique advantages as a therapy targeting the central nervous system (CNS). We aimed to investigate and summarize the potential applications of FUS in the context of spinal cord diseases. Search strategies were
Ryan Nguyen   +7 more
doaj   +2 more sources

Diagnostic and Prognostic Value of Serum Neurofilament Light Chain in Canine Spinal Cord Diseases [PDF]

open access: yesVeterinary Sciences
This study evaluated serum neurofilament light chain (NfL) as a biomarker for spinal cord diseases in dogs, including 46 healthy dogs and 76 with conditions, such as intervertebral disc herniation (IVDH), syringomyelia (SM), fibrocartilaginous embolism ...
Chaerin Kim   +4 more
doaj   +2 more sources

Spinal Cord Vascular Disease

open access: diamondAdvances in Bioscience and Clinical Medicine, 2017
This chapter describes the two main disease entities affecting the spinal cord vasculature, spinal cord ischemia, and spinal vascular malformation.
Abdoreza Ghoreishi
  +5 more sources

Prevalence of Cervical and Thoracic Spinal Disease: A Systematic Review [PDF]

open access: yesJournal of Minimally Invasive Spine Surgery and Technique, 2023
Objective This study aimed to comprehensively assess the prevalence and distribution of degenerative cervical and thoracic diseases with compression of the spinal cord, such as disc herniation (TDH) or hypertrophied ligamentum flavum causing stenosis, by
Chang-Il Ju   +3 more
doaj   +1 more source

Edaravone Modulates Neuronal GPX4/ACSL4/5-LOX to Promote Recovery After Spinal Cord Injury

open access: yesFrontiers in Cell and Developmental Biology, 2022
The FDA-approved drug edaravone has a neuroprotective effect on spinal cord injury (SCI) and many other central nervous system diseases. However, its molecular mechanism remains unclear.
Yilin Pang   +19 more
doaj   +1 more source

Characteristics of Pediatric Spinal Cord Injury in South Korea: A Single-Centered Study [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2022
Objective To determine the characteristics of pediatric spinal cord injury (SCI) in South Korea from 1990 to 2019. Methods This single-centered retrospective study included pediatric SCIs. Individuals were divided into the following five groups according
Wooyeung Kim   +4 more
doaj   +1 more source

Generation of dorsoventral human spinal cord organoids via functionalizing composite scaffold for drug testing

open access: yesiScience, 2023
Summary: The spinal cord possesses highly complex, finely organized cytoarchitecture guided by two dorsoventral morphogenic organizing centers. Thus, generation of human spinal cord tissue in vitro is challenging. Here, we demonstrated a novel method for
Weiwei Xue   +7 more
doaj   +1 more source

An emerging role of inflammasomes in spinal cord injury and spinal cord tumor

open access: yesFrontiers in Immunology, 2023
Spinal cord injury (SCI) and spinal cord tumor are devastating events causing structural and functional impairment of the spinal cord and resulting in high morbidity and mortality; these lead to a psychological burden and financial pressure on the ...
Jiansong Chen   +3 more
doaj   +1 more source

Complex Electrical Stimulation Systems in Motor Function Rehabilitation after Spinal Cord Injury

open access: yesComplexity, 2021
Spinal cord injury (SCI) is an existing incurable disease that brings great pain and life obstacles to patients. Spinal cord electrical stimulation is an effective means to alleviate spinal cord injury.
Jiange Kou   +5 more
doaj   +1 more source

The roles of microRNAs in spinal cord ischemia-reperfusion injury

open access: yesNeural Regeneration Research, 2022
Spinal cord ischemia/reperfusion injury is a devastating medical disorder with poor prognosis that is associated with several pathophysiological conditions. However, multiple stimuli can trigger SCII, so the underlying mechanism of this pathology has not
Feng-Shou Chen   +5 more
doaj   +1 more source

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