Results 31 to 40 of about 324,761 (353)

Feline Spinal Cord Diseases

Veterinary Clinics of North America: Small Animal Practice, 2010
The objective of this article is to review the recent literature that reports on the most common diseases affecting the spinal cord of cats, and to draw some general conclusions that will be useful to formulate diagnosis and prognosis for feline spinal patients.
openaire   +2 more sources

A potential target gene CD63 for different degrees of intervertebral disc degeneration

Scientific Reports, 2022
Understanding molecular mechanisms of intervertebral disc degeneration (IDD) and providing a novel target for the treatment of IDD have important implications. We sought to explore a new promising gene target for the treatment of IDD.
Sheng Gao, Shu Jia, Xutao Fan, Chengcan Gao, Qingwei Li, Yuxue Wu, Chunyang Meng   +6 more
doaj   +1 more source

Combined cerebellar and bilateral cervical posterior spinal artery stroke demonstrated on MRI [PDF]

, 2003
Combined cerebellar and spinal ischemic stroke is a rare, critical condition. We report a patient with combined cerebellar and bilateral posterolateral cervical spinal cord infarction due to bilateral stenosis of the vertebral arteries. MRI is the method
Brückmann, H., Hamann, Gerhard F., Liebetrau, M., Müller-Schunk, S., Reich, P., Scheuerer, W.   +5 more
core   +1 more source

GPX4 activator enhances neuroprotection and functional recovery in spinal cord injury

Journal of Orthopaedic Translation
Background: Spinal cord injury (SCI) exerts severe physical, social, and economic effects on individuals and the healthcare system. While much progress has been made in understanding the pathophysiology of SCI, the regulation of the ferroptosis master ...
Xinjie Liu, Yilin Pang, Baoyou Fan, Jiawei Zhang, Shen Liu, Xiaobing Deng, Yun Li, Ying Liu, Xu Zhang, Chenxi Zhao, Xiaoyu Wang, Xudong Wu, Luhua Lai, Shiqing Feng, Wenpeng Liu, Guangzhi Ning, Xue Yao   +16 more
doaj   +1 more source

Spinal dystonia and other spinal movement disorders

Dystonia, 2023
While traditionally considered a disorder of the basal ganglia, brainstem, and cerebellum, multiple reports have shown that spinal cord pathologies may lead to dystonia.
Shlok Sarin, Shlok Sarin, Temitope Lawal, Hesham Abboud, Hesham Abboud   +4 more
doaj   +1 more source

Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects [PDF]

, 2009
Many neurodegenerative diseases exhibit axonal pathology, transport defects, and aberrant phosphorylation and aggregation of the microtubule binding protein tau. While mutant tau protein in frontotemporal dementia and parkinsonism linked to chromosome 17
Falzone, Tomas Luis, Goldstein, Lawrence S. B., Lillo, Concepción, Rodrigues, Elizabeth M., Stokin, Gorazd B., Westerman, Eileen L., Williams, David S.   +6 more
core   +1 more source

RhoA/Rho kinase in spinal cord injury

Neural Regeneration Research, 2016
A spinal cord injury refers to an injury to the spinal cord that is caused by a trauma instead of diseases. Spinal cord injury includes a primary mechanical injury and a much more complex secondary injury process involving inflammation, oxidation ...
Xiangbing Wu, Xiao-ming Xu
doaj   +1 more source

Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis. [PDF]

, 2019
Mesenchymal stem/stromal cells (MSCs) display potent immunomodulatory and regenerative capabilities through the secretion of bioactive factors, such as proteins, cytokines, chemokines as well as the release of extracellular vesicles (EVs).
Barthe, Sylvain, Clark, Kaitlin, Farmer, Diana, Guo, Fuzheng, Kreutzberg, Nicole, Kumar, Priyadarsini, Paxton, Zachary, Pivetti, Christopher, Reed, Camille, Wang, Aijun, Wang, Yan, Zhang, Sheng   +11 more
core   +2 more sources

Targeting the SYVN1-EGFR axis: a breakthrough strategy for TKI-resistant NSCLC

Cell Death and Disease
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death. Currently, molecular targeted therapy remains a crucial approach to the treatment of NSCLC. However, the development of acquired drug resistance poses significant challenges
Xinsheng Xie, Weilai Tong, Yue Xie, Haoxin Jiang, Alan Jiang, Junming Huang, Zhili Liu, Jingjing Yu   +7 more
doaj   +1 more source

Integrated cryopreservation-thawing-transplantation platform for neural stem cell-based spinal cord injury repair

Bioactive Materials
Spinal cord injury (SCI) repair lacks clinically validated restorative therapies. Transplantation of exogenous neural stem cells (NSCs) offers significant potential for therapeutic applications; however, challenges remain, including substantial cell loss,
Jie Ren, Junjin Li, Hongda Wang, Haiwen Feng, Huaying Hao, Junyu Chen, Yuanquan Li, Zhengyu Xu, Chuanhao Li, Wang Jiang, Yan Wang, Xiaoyang Zhang, Xiaomeng Song, Guangzhi Ning, Jun Liang, Shiqing Feng   +15 more
doaj   +1 more source