Results 51 to 60 of about 2,689,938 (292)

Integrated cryopreservation-thawing-transplantation platform for neural stem cell-based spinal cord injury repair

Bioactive Materials
Spinal cord injury (SCI) repair lacks clinically validated restorative therapies. Transplantation of exogenous neural stem cells (NSCs) offers significant potential for therapeutic applications; however, challenges remain, including substantial cell loss,
Jie Ren, Junjin Li, Hongda Wang, Haiwen Feng, Huaying Hao, Junyu Chen, Yuanquan Li, Zhengyu Xu, Chuanhao Li, Wang Jiang, Yan Wang, Xiaoyang Zhang, Xiaomeng Song, Guangzhi Ning, Jun Liang, Shiqing Feng   +15 more
doaj   +1 more source

Mesenchymal stem cell grafts promote oligodendroglial differentiation after spinal cord injury [PDF]

, 2012
Transplantation of MSC into the acute injured spinal cord is sufficient to enhance oligodendroglial differentiation of endogenous spinal cord progenitor cells up to one month post-injury.
Bründl, Johannes
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

DISEASES OF THE SPINAL CORD [PDF]

, 2013
AbstractThis chapter discusses certain diseases of the anterior horn cells as they pertain to electromyography and nerve conduction studies. These include motoneuron disease,spinal muscular atrophy, Creutzfeldt-Jakob disease, poliomyelitis and polio-like syndrome, syringomyelia, multiple sclerosis, and other myelopathies.Electrophysiologic studies help
  +4 more sources

PLPP1 inhibits Wnt/β-catenin signaling via enhancing Caveolin-1/β-catenin interaction and is negatively regulated by c-Myc in osteosarcoma

Journal of Orthopaedic Translation
Background: Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents, characterized by rapid progression and poor prognosis. The molecular mechanisms underlying OS malignancy remain incompletely understood.
Jiangbo Nie, Yang Zhou, Xinsheng Xie, Jinfa Wu, Weilai Tong, Zhiguo Shu, Shijiang Wang, Jiaming Liu, Feng Yang, Zhili Liu   +9 more
doaj   +1 more source

A potential target gene CD63 for different degrees of intervertebral disc degeneration

Scientific Reports, 2022
Understanding molecular mechanisms of intervertebral disc degeneration (IDD) and providing a novel target for the treatment of IDD have important implications. We sought to explore a new promising gene target for the treatment of IDD.
Sheng Gao, Shu Jia, Xutao Fan, Chengcan Gao, Qingwei Li, Yuxue Wu, Chunyang Meng   +6 more
doaj   +1 more source

Application and prospect of radiomics in spinal cord and spine system diseases: A narrative review

Glioma, 2021
Spinal cord and spine system diseases are complex and diverse, and prognosis is often poor. Therefore, early diagnosis is essential, especially for spinal system tumors, which are malignant nervous system tumors that have the highest mortality and ...
Chao Ma, Guihuai Wang
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Arachidonic acid metabolism in spinal cord injury

Journal of Advanced Research
Background: Spinal cord injury (SCI) initiates a cascade of secondary pathological processes significantly impairs functional recovery and leads to complications such as neuropathic pain.
Xue Yao, Xinjie Liu, Wenbin Cai, Guangzhi Ning, Xu Zhang, Kailiang Zhou, Shiqing Feng   +6 more
doaj   +1 more source

RhoA/Rho kinase in spinal cord injury

Neural Regeneration Research, 2016
A spinal cord injury refers to an injury to the spinal cord that is caused by a trauma instead of diseases. Spinal cord injury includes a primary mechanical injury and a much more complex secondary injury process involving inflammation, oxidation ...
Xiangbing Wu, Xiao-ming Xu
doaj   +1 more source