Results 61 to 70 of about 324,761 (353)

Neuroprotective effect of adult hematopoietic stem cells in a mouse model of motoneuron degeneration

open access: yesNeurobiology of Disease, 2007
Degenerative spinal motor diseases, like amyotrophic lateral sclerosis, are produced by progressive degeneration of motoneurons. Their clinical manifestations include a progressive muscular weakness and atrophy, which lead to paralysis and premature ...
Carmen Cabanes   +3 more
doaj   +1 more source

Multimodal treatment for spinal cord injury: a sword of neuroregeneration upon neuromodulation

open access: yesNeural Regeneration Research, 2020
Spinal cord injury is linked to the interruption of neural pathways, which results in irreversible neural dysfunction. Neural repair and neuroregeneration are critical goals and issues for rehabilitation in spinal cord injury, which require neural stem ...
Ya Zheng   +4 more
doaj   +1 more source

The Effects of Acute Lipopolysaccharide Induced Inflammation on Spinal Cord Excitability [PDF]

open access: yes, 2018
Peripheral inflammation alters the excitability of dorsal horn interneurons and increases flexor reflex strength (Dubner & Ruda, 1992); however, its effect on the spinal stretch reflex is not well understood. The stretch reflex is a muscle contraction in
Sanghera, Puneet
core   +1 more source

Steroid profiling in male wobbler mouse, a model of Amyotrophic Lateral Sclerosis [PDF]

open access: yes, 2016
The Wobbler mouse is an animal model for human motoneuron diseases, especially amyotrophic lateral sclerosis (ALS), used in the investigation of both pathology and therapeutic treatment.
Aprahamian, Fanny   +9 more
core   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

The Effect of Gamma Irradiation on the Osteoinductivity of Demineralized Human Bone Allograft

open access: yesActa Medica Iranica, 2014
The gamma irradiation has been used for end sterilization of allograft bones and its effects with a 25 kGy dosage on the osteoinductive properties of demineralized bone allograft powder was studied.
Babak Arjmand   +5 more
doaj  

Leber hereditary optic neuropathy (LHON) in a 6-year-old boy with a transient spinal cord lesion

open access: yesThe Turkish Journal of Pediatrics
Background. Leber hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial disorder that predominantly manifests as bilateral, painless vision loss in young males.
Anıl Gök   +5 more
doaj   +1 more source

Spinal dI4 Interneuron Differentiation From Human Pluripotent Stem Cells

open access: yesFrontiers in Molecular Neuroscience, 2022
Spinal interneurons (INs) form intricate local networks in the spinal cord and regulate not only the ascending and descending nerve transduction but also the central pattern generator function.
Jia Xu   +10 more
doaj   +1 more source

Trajectory and Determinant of Functional Independence Among Patient with Traumatic and Non-Traumatic Spinal Cord Injury [PDF]

open access: yes, 2018
The level of functional independence was directly proportional to life satisfaction and quality of life in patients with spinal cord injury. By knowing the determinants that predict changes in functional independence, medical treatment and rehabilitation
Ferdiana, A. (Astri)   +5 more
core  

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