Results 111 to 120 of about 305,172 (361)
Ca2+-activated K+channels modulate microglia affecting motor neuron survival in hSOD1G93A mice [PDF]
, 2019 Amyotrophic lateral sclerosis (ALS) is a multifactorial disease characterized by the progressive degeneration of motor neurons (MN) and muscle paralysis. Despite current treatments, patients survive less than 3–5 years after the initial diagnosis.
Cocozza, Germana
core
Advanced Sensor Research, EarlyView.This review examines recent advancements in multimodal bioelectronics, emphasizing machine learning integration to enhance functionality. The application of machine learning methodologies improving biosignal processing, device adaptability, and diagnostic accuracy is discussed to introduce Machine Learning enhanced bioelectronics as a pathway toward ...
Myoungjae Oh +11 more
wiley +1 more source
Quantifying Performance of Bipedal Standing with Multi-channel EMG [PDF]
IROS 2017, 2017 Spinal cord stimulation has enabled humans with motor complete spinal cord injury (SCI) to independently stand and recover some lost autonomic function. Quantifying the quality of bipedal standing under spinal stimulation is important for spinal rehabilitation therapies and for new strategies that seek to combine spinal stimulation and rehabilitative ...
arxiv
A Brief Overview of the Cerebrospinal Fluid System and Its Implications for Brain and Spinal Cord Diseases. [PDF]
Front Hum Neurosci, 2021 Wichmann TO, Damkier HH, Pedersen M.
europepmc +1 more source
MicroRNA profiling reveals marker of motor neuron disease in ALS models [PDF]
, 2017 Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder marked by the loss of motor neurons (MNs) in the brain and spinal cord, leading to fatally debilitating weakness.
Amy J. Wegener +16 more
core +2 more sources
Advanced Science, EarlyView.PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou +7 more
wiley +1 more source
Diffusion Kurtosis Imaging maps neural damage in the EAE model of multiple sclerosis [PDF]
arXiv, 2018 Diffusion kurtosis imaging (DKI), is an imaging modality that yields novel disease biomarkers and in combination with nervous tissue modeling, provides access to microstructural parameters. Recently, DKI and subsequent estimation of microstructural model parameters has been used for assessment of tissue changes in neurodegenerative diseases and their ...
arxiv
Generalised boundary shift integral for longitudinal assessment of spinal cord atrophy
NeuroImage, 2020 Spinal cord atrophy measurements obtained from structural magnetic resonance imaging (MRI) are associated with disability in many neurological diseases and serve as in vivo biomarkers of neurodegeneration.
Ferran Prados +9 more
doaj
Sexuality of people with spinal cord injury: an issue of health education
Scientific Electronic Archives, 2015 The spinal cord injury causes loss of sensation and movement below the level of injury, damaging some important functions in the body such as motor function, bladder control, bowel and sexual dysfunction.
L. R. Cruz +2 more
doaj +1 more source
Using Deep Learning to Detect Spinal Cord Diseases on Thoracolumbar Magnetic Resonance Images of Dogs. [PDF]
Front Vet Sci, 2021 Biercher A +6 more
europepmc +1 more source