Results 121 to 130 of about 125,751 (335)

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

UTX Responds to Nanotopography to Suppress Macrophage Inflammatory Response by Remodeling H3K27me3 Modification

Advanced Science, EarlyView.
Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia, He Zhang, Dingqiang Mo, Bo Xie, Hongdou Qiao, Tao Chen, Haoyue Song, Xinxin Xu, Sheng Yang   +8 more
wiley   +1 more source

The epidemiology of spine and spinal cord injuries [PDF]

Саратовский научно-медицинский журнал, 2018
The article contains domestic and foreign data reflecting epidemiological peculiarities of traumatic injuries of spine and spinal cord, their character and incidence among various population groups with respect to gender and age parameters.
Tolkachev V.S., Bazhanov S.P., Ulyanov V.Yu., Fedonnikov A.S., Ninel V.G., Salikhu Kh., Norkin I.A.   +6 more
doaj  

A novel open-source ultrasound dataset with deep learning benchmarks for spinal cord injury localization and anatomical segmentation [PDF]

arXiv
While deep learning has catalyzed breakthroughs across numerous domains, its broader adoption in clinical settings is inhibited by the costly and time-intensive nature of data acquisition and annotation. To further facilitate medical machine learning, we present an ultrasound dataset of 10,223 Brightness-mode (B-mode) images consisting of sagittal ...
arxiv  

The Spinal Cord Injury Center of the Veterans Administration Hospital, Long Beach, California, U.S.A. [PDF]

, 1967
Ernest Bors
openalex   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source

Venous thrombosis and pulmonary embolism in spinal cord injury [PDF]

, 1968
Norval Watson
openalex   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

Spinal deformity after spinal cord injury [PDF]

, 1969
T McSweeney
openalex   +1 more source

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source