Results 101 to 110 of about 670,877 (408)

Neurotropin exerts neuroprotective effects after spinal cord injury by inhibiting apoptosis and modulating cytokines

Journal of Orthopaedic Translation, 2021
Background/objective: Spinal cord injury (SCI) severely and irreversibly damages the central nervous system. Neurotropin (NTP), a nonprotein extract obtained from inflamed rabbit skin inoculated with vaccinia virus, is a drug that has been used for more ...
Xue Yao, Chao Sun, Baoyou Fan, Chenxi Zhao, Yan Zhang, Huiquan Duan, Yilin Pang, Wenyuan Shen, Bo Li, Xu Wang, Chang Liu, Hengxing Zhou, Xiaohong Kong, Shiqing Feng   +13 more
doaj  

The transcriptional response of neurotrophins and their tyrosine kinase receptors in lumbar sensorimotor circuits to spinal cord contusion is affected by injury severity and survival time.

Frontiers in Physiology, 2013
Traumatic spinal cord injury (SCI) results in changes to the anatomical, neurochemical, and physiological properties of cells in the central and peripheral nervous system.
M Tyler Hougland, M Tyler Hougland, Benjamin J Harrison, Benjamin J Harrison, David S.K. Magnuson, Eric Christian Rouchka, Jeffrey C Petruska, Jeffrey C Petruska   +7 more
doaj   +1 more source

High-resolution investigation of spinal cord and spine [PDF]

arXiv, 2017
High-resolution non-invasive 3D study of intact spine and spinal cord morphology on the level of complex vascular and neuronal organization is a crucial issue for the development of treatments for the injuries and pathologies of central nervous system (CNS). X-ray phase contrast tomography enables high quality 3D visualization in ex-vivo mouse model of
arxiv  

Electrical spinal cord stimulation must preserve proprioception to enable locomotion in humans with spinal cord injury

Nature Neuroscience, 2018
Epidural electrical stimulation (EES) of the spinal cord restores locomotion in animal models of spinal cord injury but is less effective in humans.
Emanuele Formento, K. Minassian, Fabien B. Wagner, Jean-Baptiste Mignardot, Camille G. Le Goff-Mignardot, Andreas Rowald, J. Bloch, S. Micera, M. Capogrosso, G. Courtine   +9 more
semanticscholar   +1 more source

Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma [PDF]

, 2009
In this study, we evaluated the effect of green tea extract (that was administered 25 mg/kg intraperitoneal at 1 and 6 h after injury) in experimental animal model of spinal cord injury.
AL Klatsky, AP Amar, C Szabo, C Szabo, CH Tator, CH Tator, Concetta Crisafulli, D Liu, DA Butterfield, DM Basso, Emanuela Mazzon, G Rosa La, GD Carlson, GS Scott, GS Scott, H Akiyama, H Sung, Irene Paterniti, J Xu, JS Beckman, K Ogata, M Dona, M Endoh, M Joshi, M Serafini, Maria Galuppo, MG Salgo, MM Chan, MS Beattie, O Bar-Peled, O Nesic-Taylor, PA Townsend, Placido Bramanti, R Castro de, R Paola Di, Rosanna Di Paola, RT Peters, S Cuzzocrea, Salvatore Cuzzocrea, SF Liu, SL Carlson, SL Stover, T Genovese, T Genovese, T Genovese, T Genovese, T Genovese, T Hirvonen, T Kakuda, Tiziana Genovese, V Crespy, WG Tatton, Y Levites, Y Sato, YB Choi   +54 more
core   +2 more sources

Actuated Hydrogel Platforms To Study Brain Cell Behavior

Advanced Healthcare Materials, EarlyView.
The complex and dynamic viscoelastic properties of the brain underpin neural plasticity and overall function. Actuating hydrogel platforms support mechanistic research to elucidate how brain cells respond to dynamic microenvironments. This study reviews the mechanobiology of the brain and its impact on brain function in health and disease and describes
Kirill E. Zhurenkov, Darren Svirskis, Bronwen Connor, Jenny Malmström   +3 more
wiley   +1 more source

Microenvironment Imbalance of Spinal Cord Injury

Cell Transplantation, 2018
Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient physiology and psychology. The microenvironment of the injured spinal cord is complicated.
Baoyou Fan, Zhijian Wei, Xue Yao, Guidong Shi, Xin Cheng, Xian-hu Zhou, Hengxing Zhou, G. Ning, Xiaohong Kong, S. Feng   +9 more
semanticscholar   +1 more source

Neuroprotection and its molecular mechanism following spinal cord injury [PDF]

, 2012
Acute spinal cord injury initiates a complex cascade of molecular events termed 'secondary injury', which leads to progressive degeneration ranging from early neuronal apoptosis at the lesion site to delayed degeneration of intact white matter tracts ...
Liu, Nai-Kui, Xu, Xiao-Ming
core   +2 more sources

CircAars‐Engineered ADSCs Facilitate Maxillofacial Bone Defects Repair Via Synergistic Capability of Osteogenic Differentiation, Macrophage Polarization and Angiogenesis

Advanced Healthcare Materials, EarlyView.
Schematic representation of circAars‐engineered‐ADSCs incorporated into GelMA scaffolds for craniomaxillofacial bone regeneration. CircAars‐engineered ADSCs embedded in GelMA scaffolds enhance the repair of critical‐sized bone defects by binding miR‐128‐3p in the cytoplasm, thereby inhibiting its activity.
Yi He, Yunyang Lu, Runze Li, Yuquan Tang, Weidong Du, Lejia Zhang, Jie Wu, Kechen Li, Weijie Zhuang, Shiyu Lv, Yaoling Han, Bailong Tao, Feilong Deng, Wei Zhao, Dongsheng Yu   +14 more
wiley   +1 more source

Quantifying Performance of Bipedal Standing with Multi-channel EMG [PDF]

IROS 2017, 2017
Spinal cord stimulation has enabled humans with motor complete spinal cord injury (SCI) to independently stand and recover some lost autonomic function. Quantifying the quality of bipedal standing under spinal stimulation is important for spinal rehabilitation therapies and for new strategies that seek to combine spinal stimulation and rehabilitative ...
arxiv