Results 151 to 160 of about 732,175 (355)

Assisting hand function after spinal cord injury with a fabric-based soft robotic glove

Journal of NeuroEngineering and Rehabilitation, 2018
Spinal cord injury is a devastating condition that can dramatically impact hand motor function. Passive and active assistive devices are becoming more commonly used to enhance lost hand strength and dexterity. Soft robotics is an emerging discipline that
L. Cappello, J. Meyer, Kevin C. Galloway, Jeffrey D. Peisner, R. Granberry, Diana Wagner, Sven Engelhardt, S. Paganoni, C. Walsh   +8 more
semanticscholar   +1 more source

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

Advanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos, Xavier Barceló, M. Gabriella Chiariello, Irene Sanz, Amaia Iturrospe, Arantxa Arbe, J. Alberto Ortega, Siewert J. Marrink, Aitziber L. Cortajarena, Zaida Álvarez, Ivan R. Sasselli   +10 more
wiley   +1 more source

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

Advanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi, Yang‐Xun Zhang, Jun‐Yi Chen, Sai Ma, Wei‐Xuan Xue, Wei Li, Qian‐Xiao Li, Bo Song, Ya‐Ting Li, Hong‐Yu Ma, Shu‐Tao Xie, Hong‐Zhao Li, Di‐Jun Chen, Qi‐Peng Zhang, Hui‐Jie Ma, Jian‐Jun Wang, Lei Yu, Xiao‐Yang Zhang, Jing‐Ning Zhu   +18 more
wiley   +1 more source

The Lived Experience of Persons with Spinal Cord Injuries Engaging in Remote Work: A South African Perspective [PDF]

, 2023
Alicia Swart, Jerome Peter Fredericks, Lee‐Ann Jacobs‐Nzuzi Khuabi   +2 more
openalex   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Activity-based recovery training with spinal cord epidural stimulation improves standing performance in cervical spinal cord injury

Journal of NeuroEngineering and Rehabilitation
Background Individuals with a clinically complete spinal cord injury are unable to stand independently without external assistance. Studies have shown the combination of spinal cord epidural stimulation (scES) targeted for standing with activity-based ...
Claudia A. Angeli, Enrico Rejc, Beatrice Ugiliweneza, Maxwell Boakye, Gail F. Forrest, Katelyn Brockman, Justin Vogt, Brittany Logsdon, Katie Fields, Susan J. Harkema   +9 more
doaj   +1 more source

Effects of Transplanted Heparin-Poloxamer Hydrogel Combining Dental Pulp Stem Cells and bFGF on Spinal Cord Injury Repair [PDF]

, 2018
Lihua Luo, Abdullkhaleg Ali Albashari, Xiaoyan Wang, Ling Jin, Yanni Zhang, Lina Zheng, Jianjian Xia, Helin Xu, Ying‐Zheng Zhao, Jian Xiao, Yan He, Qingsong Ye   +11 more
openalex   +1 more source

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

Advanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li, Maoxiang Xu, Boyu Cai, Xiangyu Li, Zhanping Liang, Xiaohuan Xia, Haitao Zhang, Zhiwen Zhang, Fei Tan, Jialin Charlie Zheng   +9 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

A Programmable, 3D Neuron‐On‐Chip Platform Integrating Near Real‐Time Biosensing and Multiaxial Loading for Mechanobiological Injury Profiling

Advanced Science, EarlyView.
A programmable 3D Neuron‐Injury‐on‐a‐Chip platform integrates multiaxial mechanical loading with ultrasensitive electrochemical biosensing to decode neuronal responses in real time. By mimicking physiologically relevant extension–torsion forces, the system reveals load‐specific biomarker trajectories (T‐Tau, NFL), gene regulation, and apoptosis.
Sultan Khetani, Kar Wey Yong, Mawafag F. Alhasadi, Amir Hamedzadeh, Leila Shahsavari, Atefeh Rafiei, Kalvin Wu, Omakhowa Agbojo, Anupriya Singh, Kunal Karan, Salvatore Federico, Arindom Sen, Amir Sanati‐Nezhad   +12 more
wiley   +1 more source