Results 151 to 160 of about 670,877 (408)

A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A report of the TASK3‐WG1C: Phenotyping working group of the ILAE/AES joint translational task force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski   +3 more
wiley   +1 more source

Utilisation de la substitution sensorielle par électro-stimulation linguale pour la prévention des escarres chez les paraplégiques. Etude préliminaire [PDF]

open access: yesL'escarre 30 (2006) 24-37, 2006
Pressure ulcers are recognized as a major health issue in individuals with spinal cord injuries and new approaches to prevent this pathology are necessary. An innovative health strategy is being developed through the use of computer and sensory substitution via the tongue in order to compensate for the sensory loss in the buttock area for individuals ...
arxiv  

Epidemiologic evidence of spinal cord injury in Tamil Nadu, India [PDF]

open access: yes, 2017
Background:Spinal cord injury is a fearsome disability leading to increased rate of morbidity and mortality. Information about the incidence of spinal cord injury may provide support for the healthcare advancements.
Anuswedha, Ananthan   +4 more
core   +1 more source

Optimizing Filter-Probe Diffusion Weighting in the Rat Spinal Cord for Human Translation [PDF]

open access: yes, 2017
Diffusion tensor imaging (DTI) is a promising biomarker of spinal cord injury (SCI). In the acute aftermath, DTI in SCI animal models consistently demonstrates high sensitivity and prognostic performance, yet translation of DTI to acute human SCI has ...
Brian D. Schmit   +5 more
core   +3 more sources

Spinal Cord Stimulation for Spinal Cord Injury

open access: yes, 2023
Spinal cord injury is a medically complex and life-disrupting condition, associated with very high mortality rates (early death rates after admission range from 4 to 20%). In addition, it’s complicated subsequent severe disability due to the development of early or late complications.
Emil, Isagulyan,   +2 more
openaire   +2 more sources

Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models

open access: yesAdvanced Science, EarlyView.
This work introduces wireless‐powered fully implantable spinal cord stimulation (SCS) in freely moving animal models, supporting diverse ethological paradigms. kHz stimulation with real‐time digital programming offers versatile, dynamically optimized therapy. Scalable fabrication ensures high N studies and seamless translation.
Allie J. Widman   +11 more
wiley   +1 more source

Prévention des escarres chez les paraplégiques : une nouvelle approche par électrostimulation linguale [PDF]

open access: yesActes de la 4\`eme Conf\'erence Handicap 2006 "Nouvelles Technologies au service de l'homme" (2006) 216-220, 2007
Pressure ulcers are recognized as a major health issue in individuals with spinal cord injuries and new approaches to prevent this pathology are necessary. An innovative health strategy is being developed through the use of computer and sensory substitution via the tongue in order to compensate for the sensory loss in the buttock area for individuals ...
arxiv  

Cell biology of spinal cord injury and repair.

open access: yesJournal of Clinical Investigation, 2017
Spinal cord injury (SCI) lesions present diverse challenges for repair strategies. Anatomically complete injuries require restoration of neural connectivity across lesions.
T.M. O’Shea, J. Burda, M. Sofroniew
semanticscholar   +1 more source

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun   +10 more
wiley   +1 more source

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