Results 171 to 180 of about 710,546 (383)

Doing it Well: Education to Promote Satisfaction with Sexual Intimacy for People with Spinal Cord Injury [PDF]

open access: yes, 2013
Physical and psychosocial effects of a spinal cord injury may lead to concerns and difficulty with sexual satisfaction, exploration, and arousal as well as diminished confidence with participation in intimate relationships (Craig Hospital, 2012). Current
Duggan, Allison   +4 more
core   +1 more source

A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds

open access: yesAdvanced Science, EarlyView.
pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou   +7 more
wiley   +1 more source

Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

open access: yesAdvanced Science, EarlyView.
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang   +8 more
wiley   +1 more source

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv   +8 more
wiley   +1 more source

Spinal Cord Injury

open access: yesJournal of Pediatric Rehabilitation Medicine, 2012
Chellamani Harini, N. Paul Rosman
openaire   +5 more sources

Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke

open access: yesAdvanced Science, EarlyView.
Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber   +6 more
wiley   +1 more source

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

open access: yesAdvanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang   +13 more
wiley   +1 more source

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