Results 81 to 90 of about 732,175 (355)

Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury. [PDF]

, 2010
Although axonal regeneration after CNS injury is limited, partial injury is frequently accompanied by extensive functional recovery. To investigate mechanisms underlying spontaneous recovery after incomplete spinal cord injury, we administered C7 spinal ...
Beattie, Michael S, Bresnahan, Jacqueline C, Brock, John H, Courtine, Gregoire, Edgerton, V Reggie, Ferguson, Adam R, Havton, Leif A, Jindrich, Devin L, Miller, Darren M, Nout, Yvette S, Rosenzweig, Ephron S, Roy, Roland R, Strand, Sarah C, Tuszynski, Mark H   +13 more
core  

Metabolic profile of injured human spinal cord determined using surface microdialysis. [PDF]

, 2016
The management of patients having traumatic spinal cord injury (TSCI) would benefit from understanding and monitoring of spinal cord metabolic states. We hypothesized that the metabolism of the injured spinal cord could be visualized using Kohonen self ...
Awad, Bethea, Cozzens, Cripps, Fehlings, Hutchinson, Kohonen, Nelson, Phang, Phang, Phang, Timofeev, Werndle, Werndle   +13 more
core   +1 more source

Correlation Analysis Between Magnetic Resonance Imaging-Based Anatomical Assessment and Behavioral Outcome in a Rat Contusion Model of Chronic Thoracic Spinal Cord Injury

Frontiers in Neuroscience, 2022
Although plenty of evidences from preclinical studies have led to potential treatments for patients with spinal cord injury (SCI), the failure to translate promising preclinical findings into clinical advances has long puzzled researchers.
Cong Xing, Cong Xing, Cong Xing, Zeyu Jia, Zeyu Jia, Zeyu Jia, Haodong Qu, Haodong Qu, Haodong Qu, Song Liu, Song Liu, Song Liu, Wang Jiang, Hao Zhong, Hao Zhong, Hao Zhong, Mi Zhou, Mi Zhou, Mi Zhou, Shibo Zhu, Shibo Zhu, Shibo Zhu, Guangzhi Ning, Guangzhi Ning, Guangzhi Ning, Shiqing Feng, Shiqing Feng, Shiqing Feng   +27 more
doaj   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

Advanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang   +7 more
wiley   +1 more source

Developing a spinal cord injury rehabilitation service in Madagascar [PDF]

, 2018
Rehabilitation for people with spinal cord injury in many low- and middle-income countries is not avail-able or is in the early stages of development. However, rehabilitation is recognized as crucial in order to optimize functional recovery and outcomes ...
Chamberlain, MA, Hariharan, R, Locke, HN, O'Connor, RJ, Renaud, R   +4 more
core   +2 more sources

International surveillance study in acute spinal cord injury confirms viability of multinational clinical trials

BMC Medicine, 2022
Background The epidemiological international landscape of traumatic spinal cord injury (SCI) has evolved over the last decades along with given inherent differences in acute care and rehabilitation across countries and jurisdictions.
Lucie Bourguignon, Bobo Tong, Fred Geisler, Martin Schubert, Frank Röhrich, Marion Saur, Norbert Weidner, Rüdiger Rupp, Yorck-Bernhard B. Kalke, Rainer Abel, Doris Maier, Lukas Grassner, Harvinder S. Chhabra, Thomas Liebscher, Jacquelyn J. Cragg, EMSCI study group, John Kramer, Armin Curt, Catherine R. Jutzeler   +18 more
doaj   +1 more source

Olfactory Ensheathing Cells for Spinal Cord Injury: The Cellular Superpowers for Nerve Repair [PDF]

, 2022
Francesca Oieni, Ronak Reshamwala, James A. St John   +2 more
openalex   +1 more source

Battery‐Free Dual‐Channel Wireless Neurostimulator Using Passive Circuitry for Neuropathic Pain Modulation

Advanced Healthcare Materials, EarlyView.
A compact, wireless neural stimulator featuring a novel tapping inductor enables selective and independent stimulation of the motor cortex in rats via a single receiver coil. This minimally invasive system effectively reduces neuropathic pain through targeted cortical activation, offering a new avenue for bioelectronic pain therapies and advancing ...
Jeongju Moon, Kyungmo Seong, Hyeon Gyu Kim, Wonki Mun, Seung Hyun Min, Sung‐Yun Park, Joonsoo Jeong, Chin Su Koh, Hyun Ho Jung, Kyungsik Eom   +9 more
wiley   +1 more source

Spinal Progenitor-Laden Bridges Support Earlier Axon Regeneration Following Spinal Cord Injury. [PDF]

, 2018
Impact statementSpinal cord injury (SCI) results in loss of tissue innervation below the injury. Spinal progenitors have a greater ability to repair the damage and can be injected into the injury, but their regenerative potential is hampered by their ...
Anderson, Aileen J, Carlson, Mitchell A, Cummings, Brian J, Dumont, Courtney M, Munsell, Mary K, Shea, Lonnie D   +5 more
core   +1 more source

Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri, Renata Maia, Pei Zhang, Liliana Agresti, Jelmer Sjollema, Mohammad‐Ali Shahbazi, Hélder A. Santos   +6 more
wiley   +1 more source