Results 101 to 110 of about 63,554 (339)

Case Report: Hemorrhage into an Occult Spinal Ependymoma after Epidural Anesthesia [PDF]

, 2008
Epidural anesthesia is a procedure which is well tolerated and has a low incidence of adverse events. In performing caesarean sections, regional anesthesia (spinal or epidural) is the preferred modality for anesthetic delivery.
Campbell MD, Peter G., Harrop MD, James S., Ratliff MD, John K., Sharan MD, Ashwini D., Vaccaro MD, Alex R.   +4 more
core   +1 more source

Multiple myeloma presenting as spinal cord compression: a case report [PDF]

, 2010
Introduction Spinal cord compression is a potentially devastating condition that demands immediate attention. Efforts must be divided between addressing the symptoms of cord compression and identifying the precise etiology of the condition.
Chayan Chakraborti, Kristen L Miller
core   +3 more sources

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

Advanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen, Qingwei Zeng, Tangchang Xu, Xinyue Qi, Kaiyi Li, Jing Wei, Liang Hao   +6 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Predicting blunt cerebrovascular injury in pediatric trauma: Validation of the Utah Score [PDF]

, 2017
Risk factors for blunt cerebrovascular injury (BCVI) may differ between children and adults, suggesting that children at low risk for BCVI after trauma receive unnecessary computed tomography angiography (CTA) and high-dose radiation.
Akbari, Hassan, Birkas, Yekaterina, Bollo, Robert J, Gannon, Stephen, Jea, Andrew, Kestle, John R, Limbrick, David D, Jr, Naftel, Robert P, Prather, Colin T, Ravindra, Vijay M, Riva-Cambrin, Jay, Shannon, Chevis, Sivakumar, Walavan, Yang, George L   +13 more
core   +2 more sources

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Stereotactic Irradiation of Neoplasms of Spinal Localization. Literature Review and Experience of N.N. Burdenko Neurosurgical Center. Part 1. Radiosurgical Treatment of Benign Primary Tumors and Vascular Malformations of the Spinal Cord and Spine

, 2023
Andrey Golanov, Natalia Antipina, E R Vetlova, S V Zolotova, Mikhail Galkin, A. I. Lestrovaya   +5 more
openalex   +2 more sources

A Rule Based Classification Model to Predict Colon Cancer Survival [PDF]

, 2015
Introduction: Colon cancer is the second most common cancer in the world and fourth most common cancer in both sexes in Iran, whose % 8.12 of all cancers in the covers.
Abbasi, Reza, Amiri gharghani, Majid, Montazeri, Mitra, Zare, Mohammad   +3 more
core  

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Clinical characteristics and molecular mechanisms underlying bladder cancer in individuals with spinal cord injury: a systematic review

BMC Urology
Background Patients with spinal cord injury have a relatively high risk for bladder cancer and often complicated with bladder cancer in advanced stages, and the degree of aggressiveness of malignancy is high.
Xin-Lei Wang, Yi-Xuan Wang, Jun-Zhi Chen, Xin-Yu Liu, Xing Liu, Qi-Kai Zhong, Zi-Lin Zhao, Zhen-Duo Shi, Cong-Hui Han   +8 more
doaj   +1 more source