Results 111 to 120 of about 296,292 (322)

Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges

open access: yesAdvanced NanoBiomed Research, EarlyView.
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou   +7 more
wiley   +1 more source

Segmentation of cortical bone, trabecular bone, and medullary pores from micro‐CT images using 2D and 3D deep learning models

open access: yesThe Anatomical Record, EarlyView.
Abstract Computed tomography (CT) enables rapid imaging of large‐scale studies of bone, but those datasets typically require manual segmentation, which is time‐consuming and prone to error. Convolutional neural networks (CNNs) offer an automated solution, achieving superior performance on image data.
Andrew H. Lee   +3 more
wiley   +1 more source

Case Report and Literature Review of Acute Spontaneous Intraspinal Epidural Hematoma (SSEH) Secondary to Myeloproliferative Disease

open access: yesInternational Medical Case Reports Journal
Qinghao Liu,* Weiwen Zhao,* Hao Yin Department of Orthopedic, The First Affiliated Hospital of Hunan Normal University Hunan Provincial People’s Hospital, Changsha, China Mainland (PRC)*These authors contributed equally to this ...
Liu Q, Zhao W, Yin H
doaj  

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

open access: yesArthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek   +7 more
wiley   +1 more source

Associations Between Changes in Pain Sensitization and Disease Activity Following Disease‐Modifying Antirheumatic Drug Therapy in Established Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Abnormalities in pain regulatory mechanisms are common in patients with rheumatoid arthritis (RA). We investigated whether pain sensitization changes after treatment with a disease‐modifying antirheumatic drug (DMARD) and explored associations between changes in pain sensitization and disease activity.
Burcu Aydemir   +10 more
wiley   +1 more source

How Growth Cones Sense Extracellular Cues and Drive Neuronal Migration

open access: yesBioEssays, EarlyView.
Migrating neurons and growing axons utilize structurally and functionally similar growth cones to detect guidance cues. Shared receptors and signaling pathways mediate cytoskeletal reorganization to direct movement. This conserved mechanism underlies both neuronal migration and axon extension, providing insights into neuronal development and potential ...
Takahiro Kanzawa   +3 more
wiley   +1 more source

Clinical analysis of spinal hemangioblastoma: report of 7 cases with litertures review

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To summarize the treatment experiences and surgical measure and efficacy of spinal hemangioblastoma. Methods and Results The surgical experiences of 7 patients with spinal hemangioblastoma from February 2012 to February 2017 in Tianjin Huanhu ...
Huan⁃yu WANG   +3 more
doaj  

The Impact of Tirabrutinib Monotherapy for the Treatment of Bing‐Neel Syndrome: A Multicenter Retrospective Study

open access: yes
American Journal of Hematology, EarlyView.
Masuho Saburi   +19 more
wiley   +1 more source

Mitochondrial Microproteins: Emerging Regulators in Neurodevelopment and Neurodegeneration

open access: yesBioEssays, EarlyView.
Mitochondrial microproteins have emerged as critical regulators of mitochondrial function. Neurons are highly dependent on mitochondria to sustain their function. Mitochondrial microproteins can be deregulated and can contribute to the pathogenesis of neurodegenerative disorders. Mitochondrial microproteins are involved in neuronal development. However,
Nada Borghol   +2 more
wiley   +1 more source

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