Results 141 to 150 of about 296,292 (322)

INTRAMEDULLARY SPINAL CORD ABSCESS IN COMBINATION WITH NEOPLASMS (CASE REPORT)

open access: yes
In this article a case of intramedullary abscess in a 4-year-old girl is presented. Based on the anamnesis, clinical, neurological and instrumental studies, a diagnosis was established and surgical intervention was performed. In the postoperative period, a spinal cord neoplasm was detected against the background of an abscess based on histological ...
openaire   +2 more sources

Mitotane Treatment for Malignant Leydig Cell Tumor: A Case Report

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Leydig cell tumors (LCTs), constituting 1%–3% of testicular tumors, are mostly benign, but malignant cases present treatment challenges. We report a malignant LCT case with a notable response to mitotane. Case Presentation A 43‐year‐old male presented with a right testicular induration and was diagnosed with a Leydig cell tumor ...
Daiki Katsura   +7 more
wiley   +1 more source

A Case of Drug‐Induced Hypersensitivity Syndrome Caused by Apalutamide

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Apalutamide, an androgen receptor antagonist for prostate cancer, rarely causes drug‐induced hypersensitivity syndrome (DIHS). Case Presentation A 75‐year‐old male with prostate cancer and multiple bone metastases developed grade 2 rash and grade 3 liver dysfunction according to the Common Terminology Criteria for Adverse Events ...
Yuki Tanaka   +5 more
wiley   +1 more source

Metagenomic Next‐Generation Sequencing for Diagnosing Challenging Disseminated Tuberculosis: A Case Report

open access: yesiLABMED, EarlyView.
This paper presents a case of hematogenous disseminated pulmonary tuberculosis diagnosed with the aid of metagenomic next‐generation sequencing technology. The tuberculosis infection involves both lungs, the left sacroiliac joint, and the brain, with imaging demonstrating marked improvement of the lesions following anti‐tuberculosis therapy. This study
Zhipeng Zhao   +3 more
wiley   +1 more source

New insights into applications of base editor in hereditary disorders

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai   +8 more
wiley   +1 more source

Critical mistakes in managing chronic constipation in the older person and how to avoid them: A narrative review

open access: yesJournal of General and Family Medicine, EarlyView.
Abstract Objectives This narrative review identifies pitfalls in managing constipation in older adults and provides evidence‐based recommendations to avoid them. Methods A selective literature search was conducted across electronic databases (PubMed, MEDLINE, Embase, and Cochrane Library) to identify relevant publications on constipation management in ...
Madunil Niriella   +3 more
wiley   +1 more source

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