Results 201 to 210 of about 296,292 (322)

H3F3B p.K27I-mutant diffuse midline glioma is a distinct subtype of H3K27-altered diffuse midline glioma. [PDF]

Acta Neuropathol Commun
Cheng L, Zhou M, Luo T, Dong R, Chen N, Cai X, Wang X, Wu H, Chen Z, Wang Z, Qi X, Lu D, Teng L, Jian F, Wang L.   +14 more
europepmc   +1 more source

Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Age‐related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD) are an increasing public health concern. Whereas the pathology of these diseases is complex, chronic central inflammation, or neuroinflammation, is commonly observed across many neurodegenerative diseases ...
Alex Foster‐Powell, Amin Rostami‐Hodjegan, Guy Meno‐Tetang, Donald E. Mager, Kayode Ogungbenro   +4 more
wiley   +1 more source

BurstDR™ spinal cord stimulation for chemotherapy-induced peripheral neuropathy. [PDF]

Surg Neurol Int
Jaffee S, Mamagdi J, Vaezi M, Kite T, Gupta B, Valleta S, Monaco F, Tomycz N.   +7 more
europepmc   +1 more source

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna, Amitava Mitra, Matthew L. Zierhut, Lilly East, Chandra Durairaj   +4 more
wiley   +1 more source

Rare case of spontaneous predominantly posterior infarction of the conus medullaris: MRI clears the dilemma. [PDF]

J Neurol
Forbrig R, Rangan K, Schindler A.
europepmc   +1 more source

Embelin Mitigates the Impact of Perinatal Inflammation on Neuron Development by Inhibiting 5‐Lipoxygenase‐Mediated Ferroptosis

Phytotherapy Research, EarlyView.
ABSTRACT Neuronal development in newborns is often constrained by perinatal inflammation, with limited research available on the pathogenesis and treatment strategies for this condition. This study aimed to investigate the neuroprotective effects of Embelin in mitigating perinatal inflammation‐induced neuronal development limitations by targeting 5 ...
Feng Zhang, Mengya Sun, Shiyi Ma, Junfang Sun, Yishi Li, Xianghong Li, Hong Jiang   +6 more
wiley   +1 more source

BioGlue^® Induced Mass Formation Aggravating Spinal Canal Invasion After Intradural Tumor Surgery. [PDF]

J Clin Med
Jang SW, Lee SH, Shin HK, Jeon SR, Park D, Kim C, Park JH.   +6 more
europepmc   +1 more source

µCodes: A Universal Grid Platform for Microscale Mapping, Microscopy Navigation, and Multimodal Imaging

Small, EarlyView.
µCodes, a microgrid system designed to enhance sample navigation, alignment, and co‐registration of images obtained from various optical and electron microscopy techniques, is presented. µCodes is a platform for tracking and locating targets or cells of interest across different imaging modalities with high precision.
Aref Valipour, Jungmin Ha, Stephen N. Housley   +2 more
wiley   +1 more source

Butylated hydroxytoluene (BHT) induces zebrafish spinal cord defects and scoliosis by inhibiting the hedgehog pathway. [PDF]

Sci Rep
Cheng H, Li Y, Liu F, Zhu S, Chen L, Lu H, Shi X, Huang L.   +7 more
europepmc   +1 more source

Developments of Thermosensitive Hydrogel for Maxillofacial Bone Regeneration

Small Science, EarlyView.
Thermosensitive hydrogel with seed cells and growth factors presents a new method for bone regeneration, changing states with temperature and offering fluidity, injectability, and controlled drug release. This article reviews thermosensitive hydrogel's role in angiogenesis, neurogenesis, and osteogenesis in maxillofacial bone regeneration and discusses
Qinrou Zhang, Ying Wu, Jialiang Dai, Zihan Jia, Minjia Zhu, Xinyi Li, Le Xiao, Jingyi Li, Zixiang Dai, Yuxing Bai, Jibin Song, Ke Zhang   +11 more
wiley   +1 more source