Results 261 to 270 of about 332,818 (369)

Identification of a distinct epigenetic subgroup with inferior PFS in intracranial mesenchymal tumors with FET::CREB fusion

Brain Pathology, EarlyView.
Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin, Yun Ning, Yang Lan, Yu‐Juan Cao, Rui‐Jiao Zhao, Hai‐Nan Li, Song Duan, Wei‐Wei Fu, Hai‐Bo Wu, Feng Wu, Xiu‐Wu Bian, Tao Luo, Xiao‐Hong Yao   +12 more
wiley   +1 more source

Myopericytoma of the thoracic spine in a pregnant woman: a case report on the management of a rare neoplasm. [PDF]

Einstein (Sao Paulo)
Ferreira AJ, Négri TLM, Vieira JH, Dias AA, Possa MS, Lima GBP.   +5 more
europepmc   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Intravascular large B-cell lymphoma presenting as encephalomyelitis diagnosed by renal biopsy: a case report. [PDF]

BMC Neurol
Ma J, Song D, Yu X, Wang T, Shen Y, Ma L, Wang X.   +6 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Nuances in the surgical treatment of gangliocytomas of the spinal cord: illustrative cases. [PDF]

J Neurosurg Case Lessons
Amhaz HH, Abi Faraj C, Wu AS, Rao G, Gubbiotti MA, McCutcheon IE.   +5 more
europepmc   +1 more source

The LGALS9/miR‐491‐5p Axis Regulates CD8+ T Cell Function and Inhibits the Progression of Gastric Cancer

Cancer Science, EarlyView.
In this study, we found that LGALS9 is highly expressed in gastric cancer and may affect the development of gastric cancer by participating in the infiltration of CD8+ T cells. Knockout of LGALS9 can reverse T cell function and relieve immunosuppression, and enhance the killing effect of T cells on gastric cancer cells.
Wanzhong Huang, Wei Zheng, Dagao Zhu, Zhi Sun, Wei Lu, Jun Tao, Chen Liu, Liangliang Li, Yingli Zhou, Honghong Fan, Hong Tao, Wenjuan Li   +11 more
wiley   +1 more source

Intramedullary Hemangioblastoma in the Cervical Spinal Cord of a Dog. [PDF]

Case Rep Vet Med
Arai K, Kushige H, Sakai O, Yoshitake R, Kutara K, Sugimoto K, Akashi N, Nakamura S, Sugiyama A.   +8 more
europepmc   +1 more source

A summary of the status of de novo cancer in transplant recipients. [PDF]

, 1972
Penn, I, Starzl, TE
core  

Effectiveness and Safety of Radium‐223 for Bone‐Metastatic Castration‐Resistant Prostate Cancer: The KYUCOG‐1901 Study

Cancer Science, EarlyView.
The KYUCOG‐1901 prospective multicenter study evaluated radium‐223 in 93 Japanese patients with bone‐metastatic castration‐resistant prostate cancer. Ra‐223 was well tolerated, produced meaningful declines in ALP, and yielded a median overall survival of 23.0 months. Early initiation in patients with lower disease burden and integration with subsequent
Masaki Shiota, Shuichi Tatarano, Tomomi Kamba, Toshiyuki Kamoto, Tsukasa Igawa, Naoya Masumori, Hirotsugu Uemura, Kensuke Mitsunari, Takayuki Sumiyoshi, Hiroji Uemura, Katsuyoshi Higashijima, Shoji Tokunaga, Masatoshi Eto   +12 more
wiley   +1 more source