Results 51 to 60 of about 296,292 (322)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Postoperative radiation for primary melanoma of the cervical spinal cord in a pregnant patient: A case report & review of the literature

Interdisciplinary Neurosurgery, 2018
Only 1% of melanomas present with isolated involvement of the central nervous system. Primary melanoma of the spinal cord is especially rare. There are only a handful of cases reported and only one reported during pregnancy. The patient was a 27-year-old
Samantha Stubbs, BS, Haris Vakil, BS, Gary D. Lewis, MD, Sarah A. Westergaard, MD, Gerald A. Campbell, MD, PhD, Todd A. Swanson, MD, PhD   +5 more
doaj   +1 more source

Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor‐Stroma Co‐Culture Model

Advanced Healthcare Materials, EarlyView.
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret, Jean‐Baptiste Billeau, Michael H. Weber, Derek H. Rosenzweig, Stephan Reuter   +4 more
wiley   +1 more source

A Targeted Redox‐Active Dual‐Action Pt(IV)‐Mn(II) Prodrug Displays Enhanced In Vivo Anticancer Activity

Advanced Healthcare Materials, EarlyView.
A new oxaliplatin‐based Pt(IV) prodrug bearing a Mn(II) superoxide dismutase mimic is synthesized and studied, in vitro and in vivo, in the context of colorectal cancer. Encapsulation of this prodrug in an easy‐to‐implement PEGylated micelle formulation demonstrated the highest in vivo anticancer activity among all the tested conditions, supporting the
Alvaro Lopez‐Sanchez, Henri Chédotal, Ram Pravin Kumar Muthuramalingam, Marine Thomas, Jia Ning Nicolette Yau, Priya Ranjan Sahoo, Clotilde Policar, Frédéric Batteux, Kadda Medjoubi, Andrea Somogyi, Giulia Adriani, Carole Nicco, Romain Coriat, Giorgia Pastorin, Hélène C. Bertrand   +14 more
wiley   +1 more source

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

A Comprehensive Review of Clinical Studies on Bacterial Cellulose: From the Earliest Uses to Contemporary Innovations

Advanced Healthcare Materials, EarlyView.
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier, Justin Christopher D'Antin, Gemma Julio, Anna Roig   +3 more
wiley   +1 more source

Diagnosis and treatment of spinal and spinal cord tumors in children

Chinese Journal of Contemporary Neurology and Neurosurgery
Spinal and spinal cord tumors in children are rare and often present with non-specific symptoms, leading to delayed diagnosis and potentially catastrophic consequences.
XIU Bo
doaj   +1 more source

Primary intradural extramedullary Ewing sarcoma in the lumbar area: A case report

Radiology Case Reports, 2022
Primary intradural extramedullary Ewing sarcoma (IEES) is the rarest type of Ewing sarcoma. Extreme caution is required for the diagnosis of IEES because benign intradural spinal tumors can be mistaken for IEES in the early stages of imaging and clinical
Ramin Ebrahimi, MD, Amir sajjad Mounesi sohi, MD, Ali Mirsardoo, MD, Nima Moosavi, MD, Mohammad Saeid Khonji, MD   +4 more
doaj   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source

Unusual appearance of spontaneous spinal intradural hematoma mimicking a meningioma

Radiology Case Reports
Spontaneous spinal intradural hematoma is uncommon. It can mimic vascular or hemorrhagic neoplasms, as certain imaging features overlap. The distinction between spinal hematoma and neoplasm is crucial for the approach to management and might determine ...
Akeel A. Alali, MD, FRCPC, ABR, Ali H. Alassiri, MD, FRCPC   +1 more
doaj   +1 more source