Results 71 to 80 of about 532,221 (295)

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Body image distortions following spinal cord injury [PDF]

, 2013
Background: Following spinal cord injury (SCI) or anaesthesia, people may continue to experience feelings of the size, shape, and posture of their body, suggesting that the conscious body image is not fully determined by immediate sensory signals.
Longo, Matthew R., Scivoletto, G., G. Scivoletto, Fuentes, C.T., M. R. Longo, C. T. Fuentes, Pazzaglia, M., PAZZAGLIA, Mariella, Haggard, P., P. Haggard   +9 more
core   +1 more source

Giant cell tumor of the thoracic spine: An unusual cause for spinal cord compression

Radiology Case Reports
Giant cell tumors (GCTs) of bone are uncommon neoplasms, typically located in the metaphysis of long bones, with rare occurrences in the spine, especially in the thoracic region.
Ghassen Gader, Fatma Ben Attig, Wiem Mansour, Abdelhafidh Slimane, Malek Bourgou, Mohamed Badri, Ihsèn Zammel   +6 more
doaj   +1 more source

Spinal cord anaplastic meningioma with extra-neural metastasis in a cat

Ciência Rural, 2018
: Meningiomas are the most frequent neoplasms involving the brain in dogs and cats, and are occasionally observed in the spinal cord. They cause compression of the central nervous system; however, do not infiltrate the neuropile and rarely metastasize ...
Klaus Scherer Prates, Matheus Viezzer Bianchi, Lauren Santos de Mello, Viviana Cauduro Matesco, Cíntia de Lorenzo, David Driemeier, Saulo Petinatti Pavarini   +6 more
doaj   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Omega-3 Fatty Acids Improve Recovery, whereas Omega-6 Fatty Acids Worsen Outcome, after Spinal Cord Injury in the Adult Rat [PDF]

, 2006
Spinal cord injury (SCI) is a cause of major neurological disability, and no satisfactory treatment is currently available. Evidence suggests that polyunsaturated fatty acids (PUFAs) could target some of the pathological mechanisms that underlie damage ...
King, Von R, Dyall, Simon C; id_orcid, Curran, O. E., King, V. R., Priestley, John V, Huang, W. L., Dyall, Simon, Michael-Titus, A. T., Huang, Wenlong L, Priestley, J. V., Curran, Olimpia E, Michael-Titus, Adina T   +11 more
core   +1 more source

Infiltrating Tumor versus Demyelination Disorders: Case Study of Two Adults

Indian Journal of Neurosurgery
Long-segment intramedullary spinal cord lesions pose a unique diagnostic and therapeutic dilemma from a neurosurgical perspective. For the operating surgeon, the central challenge lies in distinguishing infiltrative intramedullary tumors from ...
Harsh Rajeshbhai Patel, Preeti Singh, Abhaya Kumar   +2 more
doaj   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Feasibility of using training cases from International Spinal Cord Injury Core Data Set for testing of International Standards for Neurological Classification of Spinal Cord Injury items

, 2014
Study design: Descriptive comparison analysis. Objective: To evaluate whether five training cases of International Spinal Cord Injury Core Data Set (ISCICDS) are appropriate for testing the facts within the International Standards for Neurological ...
Hu, Z-W, Zhou, M-W, F Biering-Sørensen, Hu, Z W, Zhou, M W, Biering-Sorensen, F., Liu, N., M-W Zhou, Biering-Sørensen, F, N Liu, Liu, N, Z-W Hu   +11 more
core   +1 more source