Results 111 to 120 of about 50,813 (265)

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Porcupine‐Quill‐Inspired Shape‐Morphing Biointerfaces Disassemble Biofilms

Advanced Science, EarlyView.
A porcupine‐spine‐inspired dynamic offensive bio‐interface is developed for active biofilm disassembly. By coupling electrically driven nano‐dagger penetration with light‐triggered ROS generation, the surface overcomes the passive limitations of conventional mechano‐bactericidal topographies, achieving near‐complete biofilm eradication, strong ...
Feng Qian, Muqiu Xia, Ziyu Wang, Xinyuan Jia, Jinke Yin, Mengyu Fu, Xue Zhang, Xiao‐Lei Shi, Shiqiang Chen, Ning Wang, Zhi‐Gang Chen   +10 more
wiley   +1 more source

Digital Twins for the Design, Interactive Control, and Deployment of Modular, Fiber‐Reinforced Soft Continuum Arms

Advanced Intelligent Systems, EarlyView.
A digital twin framework is presented for modular soft continuum arms built from fiber‐reinforced pneumatic actuators. Cosserat rod models describe individual actuators, while virtual assemblies are formed through serial and parallel networks, preserving actuator‐level architecture and arm deformation.
Seung Hyun Kim, Jiamiao Guo, Arman Tekinalp, Heng‐Sheng Chang, Ugur Akcal, Tixian Wang, Darren Biskup, Benjamin Walt, Girish Chowdhary, Girish Krishnan, Prashant G. Mehta, Mattia Gazzola   +11 more
wiley   +1 more source

Design and Characterization of a Dual‐Mode Soft Robotic Flapping Propeller With Pneumatic Stiffness Modulation

Advanced Intelligent Systems, EarlyView.
A novel soft robotic propeller overcomes traditional efficiency‐flexibility tradeoffs via a hybrid pneumatic‐cable actuation strategy. This architecture enables active stiffness modulation with dual‐mode locomotion: tunable biomimetic swimming and earthworm‐inspired wriggling for confined spaces.
Jiazi Geng, Hua Shao, Yiyang Li, Lin Liang, Jinfeng Yang, Xianhong He, Fengran Xie   +6 more
wiley   +1 more source

Osteoporosis and adult spinal deformity-a review for spinal surgeons by the SRS adult spinal deformity task force on senescence. [PDF]

Spine Deform
Lord E, Vincent M, Walker CT, Osorio J, Molina C, Jones K, van Hooff M, Theologis A, Yagi M, Blakemore L, Shah S, Hu S, de M, Kleuver, Pizones J, Kelly M, Pellise F, Ames C, Eastlack R, Scoliosis Research Society Adult Spinal Deformity Task Force Senescence Committee.   +19 more
europepmc   +1 more source

Sports Activity Recognition Using Textile‐Based Sensor Fusion and Complex‐Valued Residual Convolutional Neural Networks

Advanced Intelligent Systems, EarlyView.
Motion artifacts in electrocardiographic signals, conventionally dismissed as noise, are shown to encode discriminative activity information. A smart t‐shirt fusing textile strain sensors with textile ECG electrodes, processed through a complex‐valued residual network, recognizes 12 sport activities.
Nada Al‐azzawi, Munire Sibel Cetin, Asli Tuncay Atalay, Ozgur Atalay, Gökhan Ince   +4 more
wiley   +1 more source

Retrograde Intubation in a Severe Fixed Spinal Deformity: A Case Report. [PDF]

Clin Pract Cases Emerg Med
Joshi S, Nayak S, Chakraborty S, Kaur H, Siddiqua N, Bhoi S.   +5 more
europepmc   +1 more source

Miniaturized Multifunctional Valves for Intelligent Pneumatic Systems in Soft Robotics

Advanced Intelligent Systems, EarlyView.
Miniaturized multifunctional pneumatic valves in normally closed (NC) and normally open (NO) configurations enable reconfigurable and programmable fluidic logic—including AND, OR, NAND, and NOR gates—with/without physical replumbing. These valves integrate sensing, logic, and actuation within a unified architecture, demonstrated through an electronics ...
J. Xu, X. Z. Niu, J. Andersson, D./G. Broo, K. Hjort   +4 more
wiley   +1 more source

Achieving Correction and Mitigating Complications in Adult Spinal Deformity through an Anterior-Posterior Combined Approach. [PDF]

Yonsei Med J
Kim D, Jang HJ, Moon BJ, Park JY, Ha Y, Kuh SU, Chin DK, Kim KS, Oh JK, Kim KH.   +9 more
europepmc   +1 more source

The Key Technologies and Technological Evolution Mechanisms of Robotic Systems for Fracture Reduction Surgery

Advanced Intelligent Systems, EarlyView.
This review traces three decades of technological evolution in robot‐assisted fracture reduction systems, from early robotic concepts to clinically oriented platforms. Key advances in robotic architecture, navigation, path planning, interaction control, and surgical integration are summarized, while current translational challenges and future ...
Shaolong Kuang, Xiaoyang Hu, Jianhua Li, Fang Wang, Xue Zhang, Lihai Zhang   +5 more
wiley   +1 more source