Results 91 to 100 of about 54,171 (312)

Guidelines for returning to activity after spinal deformity surgery

Returning to activity after spinal deformity surgery is vital for patient recovery and long-term health, yet there is significant variability in postoperative protocols among surgeons worldwide.
Welborn, Michelle C, Xiong, Grace X, Parent, Stefan, Hu, Serena S, Cheung, Jason PY, Cahill, Patrick J, Vaccaro, Alex R, Pellisé, Ferran, Turtle, Joel D, Mehta, Jwalant S   +9 more
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Structural and functional peculiarities of spine deformity development in neurofibromatosis NF-1

Бюллетень сибирской медицины, 2010
To study pathogenetic mechanisms of the development of spinal deformity in neurofibromatosis.Structural components of the spine were presented as specimens obtained after surgical correction of spinal deformity performed in 10 children with III—IV grade ...
A. M. Zaidman, M. V. Mikhailovsky, Ye. L. Zaviyalova, V. A. Suzdalov, M. A. Sadovoy   +4 more
doaj   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Personalizing adult spinal deformity surgery through multimodal artificial intelligence

To achieve meaningful, patient-centered outcomes following adult spinal deformity (ASD) surgery, it is crucial to engage in precise preoperative planning, perform excellent intraoperative execution, and ensure careful postoperative management.
Christopher P. Ames, Tej D. Azad, Vikas N. Vattipally   +2 more
core   +1 more source

The Use of Intralaminar Screws in Patients With Spinal Deformity

, 2013
Study Design:Retrospective study.Objective:To demonstrate that intralaminar screws (ILS) can be used as supplements in spinal deformity surgery in the thoracic and lumbar levels in pediatric and adult patients.Summary of Background Data:Rigid posterior ...
Köse, Kamil Çağrı, İnanmaz, Mustafa Erkan   +1 more
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Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Surgical treatment for adult spinal deformity: Conceptual approach and surgical strategy

Spine Surgery and Related Research, 2017
Planning of surgical treatment requires determination of whether osteoarthritis of the spine with lumbar pain should be treated as spinal canal stenosis with or without deformity or as lumbar degenerative scoliosis and clarification of whether treatment ...
Yukihiro Matsuyama
doaj   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Correlation of Spinal Deformity Index and Bone Mineral Density in Postmenopausal Osteoporotic Women

, 2004
Lumbar spine is the most frequently effected skeletal site by bone loss due to menopause in women. Therefore increased dorsal kyphosis and spinal deformity are the most common problems in postmenopausal women with spinal osteoporosis.
Aynur Metin Terzibaşoğlu, Halime Toros, Fikret Tüzün, Baha Çelik, Önder Aydıngöz, Ülkü Akarırmak, Şansın Tüzün   +6 more
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