Results 41 to 50 of about 745,068 (257)

Polyethylene microplastics promote nucleus pulposus cell senescence by inducing oxidative stress via TLR4/NOX2 axis

Ecotoxicology and Environmental Safety
This study aimed to detect and characterize microplastics in intervertebral disc and investigate their effects and molecular mechanism on intervertebral disc degeneration.
Weilin Zhang, Zhencong Li, Zhongwei Wang, Kuize Liu, Shengbang Huang, Jinguo Liang, Zhiwen Dai, Weixiong Guo, Chao Mao, Siyuan Chen, Jinsong Wei   +10 more
doaj   +1 more source

The Accuracy of 3D Printing Assistance in the Spinal Deformity Surgery

BioMed Research International, 2019
Background The pedicle screw is one of the main tools used in spinal deformity correction surgery. Robotic and navigated surgeries are usually used, and they provide superior accuracy in pedicle screw placement than free-hand and fluoroscopy-guided ...
Po-Chen Chen, Chien-Chun Chang, Hsien-Te Chen, Chia-Yu Lin, Tsung-Yu Ho, Yen-Jen Chen, Chun-Hao Tsai, Hsi-Kai Tsou, Chih-Sheng Lin, Yi-Wen Chen, H. Hsu   +10 more
semanticscholar   +1 more source

Tips and Pearls in Spinal Osteotomy [PDF]

Iranian Journal of Neurosurgery, 2022
Background and Aim: Spinal osteotomy is a general term for techniques applied to correct spinal deformity. The aims of osteotomy are to create a normal range of spine curvature, pain relief, and to improve quality of life.
Seyed Reza Mousavi, Seyed Habibollah Hassani, Ali Kazeminezhad   +2 more
doaj  

Dual S2 Alar-Iliac Screw Technique With a Multirod Construct Across the Lumbosacral Junction: Obtaining Adequate Stability at the Lumbosacral Junction in Spinal Deformity Surgery

Neurospine, 2019
To illustrate the safe placement of a 5-screw/5-rod construct across the spinopelvic junction in a complex revision case utilizing 4 S2 alar-iliac (S2AI) screws as well as an iliac screw for a kickstand rod. The S2AI screws are often used for lumbosacral
P. Park, James D. Lin, Melvin C. Makhni, Meghan Cerpa, R. Lehman, L. Lenke   +5 more
semanticscholar   +1 more source

Poly-3-hydroxybutyrate-co-3-hydroxyvalerate(PHBV)-Polyethylene glycol 20k(PEG20k) as a promising delivery system for PT2399 in the treatment of disc degeneration

Journal of Biological Engineering
Disc degeneration often leads to a highly prevalent symptom known as low back pain. Healthy nucleus pulposus tissue exhibited a hypoxic environment devoid of blood vessels, while degenerated nucleus pulposus experienced hypoxic deterioration and the ...
Zhencong Li, Weilin Zhang, Shengbang Huang, Zhiwen Dai, Jinguo Liang, Qiulan Qiu, Siyuan Chen, Weixiong Guo, Zhongwei Wang, Jinsong Wei   +9 more
doaj   +1 more source

Proximal Junctional Kyphosis and Proximal Junctional Failure Following Adult Spinal Deformity Surgery

Korean Journal of Spine, 2017
The purpose of this review is the current understanding of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) following adult spinal deformity (ASD) surgery.
S. Hyun, Byoung Hun Lee, Jong-Hwa Park, Ki-Jeong Kim, T. Jahng, Hyun-Jib Kim   +5 more
semanticscholar   +1 more source

An assessment of frailty as a tool for risk stratification in adult spinal deformity surgery.

Neurosurgical Focus, 2017
OBJECTIVE The goal of this study was to analyze the value of an adult spinal deformity frailty index (ASD-FI) in preoperative risk stratification. Preoperative risk assessment is imperative before procedures known to have high complication rates, such as
Emily Miller, Brian J. Neuman, Amit Jain, Alan H. Daniels, T. Ailon, D. Sciubba, K. Kebaish, V. Lafage, J. Scheer, Justin S. Smith, S. Bess, C. Shaffrey, C. Ames   +12 more
semanticscholar   +1 more source

Restoration of Sagittal Balance in Spinal Deformity Surgery

Journal of Korean Neurosurgical Society, 2018
The prevalence of patients with adult spinal deformity (ASD) has been reported as high as 68%. ASD often leads to significant pain and disability. Recent emphasis has been placed on sagittal plane balance and restoring normal sagittal alignment with ...
Melvin C. Makhni, J. Shillingford, Joseph L. Laratta, S. Hyun, Yongjung Kim   +4 more
semanticscholar   +1 more source

Risk Factors for Postoperative Coronal Balance in Adult Spinal Deformity Surgery

Global Spine Journal, 2018
Study Design: A retrospective case-control study. Objectives: To determine factors influencing the ability to achieve coronal balance following spinal deformity surgery.
S. Lewis, Sam G. Keshen, S. Kato, Taylor Dear, Aaron M. Gazendam   +4 more
semanticscholar   +1 more source

PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood

Mediators of Inflammation
Objectives. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease characterized by chronic spinal inflammation, arthritis, gut inflammation, and enthesitis.
Bo Han, Qiaobo Xie, Weishi Liang, Peng Yin, Xianjun Qu, Yong Hai   +5 more
doaj   +1 more source