Results 51 to 60 of about 54,171 (312)

Polyethylene microplastics promote nucleus pulposus cell senescence by inducing oxidative stress via TLR4/NOX2 axis

Ecotoxicology and Environmental Safety
This study aimed to detect and characterize microplastics in intervertebral disc and investigate their effects and molecular mechanism on intervertebral disc degeneration.
Weilin Zhang, Zhencong Li, Zhongwei Wang, Kuize Liu, Shengbang Huang, Jinguo Liang, Zhiwen Dai, Weixiong Guo, Chao Mao, Siyuan Chen, Jinsong Wei   +10 more
doaj   +1 more source

Spinal deformities and pseudofractures [PDF]

American Journal of Roentgenology, 1987
Nine children with spinal deformities had CT examinations after sustaining blunt abdominal trauma. Partial-volume averaging of two lumbar vertebrae suggested a spinal fracture in four children. All four pseudofractures were oriented in a plane perpendicular to the deformity.
openaire   +2 more sources

Kickstand rods and correction of coronal malalignment in patients with adult spinal deformity.

, 2023
PurposeCoronal malalignment (CM) is a challenging spinal deformity to treat. The kickstand rod (KR) technique is powerful for correcting truncal shift. This study tested the hypothesis that the KR technique provides superior coronal alignment correction ...
Mundis, Gregory M, Lafage, Virginie, Bess, Shay, International Spine Study Group (ISSG), Buell, Thomas J, Uribe, Juan S, Lenke, Lawrence G, Ames, Christopher P, Lafage, Renaud, Shaffrey, Christopher I, Eastlack, Robert K, Okonkwo, David O, Smith, Justin S, Walker, Corey T   +13 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Poly-3-hydroxybutyrate-co-3-hydroxyvalerate(PHBV)-Polyethylene glycol 20k(PEG20k) as a promising delivery system for PT2399 in the treatment of disc degeneration

Journal of Biological Engineering
Disc degeneration often leads to a highly prevalent symptom known as low back pain. Healthy nucleus pulposus tissue exhibited a hypoxic environment devoid of blood vessels, while degenerated nucleus pulposus experienced hypoxic deterioration and the ...
Zhencong Li, Weilin Zhang, Shengbang Huang, Zhiwen Dai, Jinguo Liang, Qiulan Qiu, Siyuan Chen, Weixiong Guo, Zhongwei Wang, Jinsong Wei   +9 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Complications of adult spinal deformity surgery: A literature review

Journal of Craniovertebral Junction and Spine, 2022
Purpose: Adult spinal deformity incidence increases accordingly as the population ages. Even though surgery is the best option for the treatment, the complications due to surgery are pretty challenging. This study aims to review the complication rates of
Nevhis Akıntürk, Mehmet Zileli, Onur Yaman   +2 more
doaj   +1 more source

Three-dimensional reconstruction using stereoradiography for evaluating adult spinal deformity: a reproducibility study. [PDF]

, 2016
PURPOSE: In addition to the sagittal alignment, impact of transverse plane parameters (TPP) and rotatory subluxation on patients reported outcomes were highlighted.
ROHAN, Pierre-Yves, SCHWAB, Frank, LAFAGE, Virginie, SKALLI, Wafa, VIRA, Shaleen, OREN, Jonathan, LAFAGE, Renaud, GUIGUI, Pierre, DELSOLE, Edward, FERRERO, Emmanuelle   +9 more
core   +1 more source

Experimental and Numerical Modal Analysis of Composite Sandwich Structures Using Surfboards as Model Systems

Advanced Engineering Materials, EarlyView.
This article presents an experimental and numerical modal investigation of composite sandwich structures using surfboards as model systems. By comparing different core materials and reinforcement strategies, the study demonstrates how local stiffeners influence vibrational response and introduce characteristic modal features, highlighting modal ...
Brett Connellan, Luca Lomazzi, Mathis Mercier, Kara Stark, Marc in het Panhuis   +4 more
wiley   +1 more source

Artificial intelligence clustering of adult spinal deformity sagittal plane morphology predicts surgical characteristics, alignment, and outcomes.

, 2023
PurposeAI algorithms have shown promise in medical image analysis. Previous studies of ASD clusters have analyzed alignment metrics-this study sought to complement these efforts by analyzing images of sagittal anatomical spinopelvic landmarks.
Gum, Jeffrey L, Schwab, Frank, International Spine Study Group (ISSG), Hostin, Richard A, Eastlack, Robert, Lafage, Renaud, Gupta, Munish, Burton, Doug, Kebaish, Khaled, Daniels, Alan H, Hamilton, D Kojo, Lafage, Virginie, Bess, Shay, Soroceanu, Alex, Passias, Peter G, Protopsaltis, Themistocles, Mundis, Gregory, Durand, Wesley M, Hart, Robert A, Shaffrey, Christopher, Kelly, Michael P, Klineberg, Eric O, Kim, Han Jo, Ames, Christopher, Smith, Justin S   +24 more
core   +1 more source