Results 181 to 190 of about 329,755 (256)

Safety of Venous Thromboembolism Prophylaxis Protocol Using a Novel Leg Exercise Apparatus in Bedridden Patients due to Spinal Diseases. [PDF]

Cureus, 2021
Kobayashi K, Shimizu Y, Haginoya A, Hada Y, Yamazaki M.   +4 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

AAD-2004, a potent spin trapping molecule and microsomal prostaglandin E synthase-1 inhibitor, shows safety and efficacy in a mouse model of ALS

, 2010
While free radicals and inflammation constitute major routes of neuronal injury occurring in neurodegenerative diseases, neither antioxidants nor nonsteroidal anti-inflammatory drugs (NSAIDs) have shown significant efficacy in human clinical trials.
Sun Park, Jae Lee, Bok Yun, Jin Lee, Jin Shin, Young Lee, Joe Springer, Sun Son, Yong Lee, Byoung Gwag, Doo Im, Soo Byun, Woong Cho   +12 more
core  

Editorial: Integrated clinical management and neurorehabilitation for lumbosacral spinal diseases. [PDF]

Front Neurol
Regmi M, Yang C.
europepmc   +1 more source

Reoperations after fusion surgeries for degenerative spinal diseases depending on cervical and lumbar regions: a national database study. [PDF]

BMC Musculoskelet Disord, 2021
Park MS, Ju YS, Moon SH, Kim YW, Jung JH, Oh JH, Kim CH, Chung CK.   +7 more
europepmc   +1 more source

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

Advanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen, Yuman Li, Chenyu Deng, Leran Li, Zhewen Hu, Boon Chin Heng, Yuting Niu, Shiyu Sun, Min Gao, Xiaopei Chi, Ying He, Mingming Xu, Ying Huang, Xuliang Deng   +13 more
wiley   +1 more source

Application of functional magnetic resonance imaging in identifying responsible brain regions associated with spinal diseases related pain. [PDF]

Front Med (Lausanne)
Zhang J, Wang N, Ren LM, Sun X, Zhang JP, Zheng Y.   +5 more
europepmc   +1 more source

Minimally Invasive Spinal Fusion Using Percutaneous Pedicle Screw Instrumentation Can Provide a Better Health-Related QOL in Early Stage Than Conventional Methods in the Treatment of Single-Level Degenerative Lumbar Spinal Diseases. [PDF]

Clin Interv Aging, 2023
Iwabuchi M, Tominaga R, Komatsu J, Shirado O.   +3 more
europepmc   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

Prevalence and breed predisposition for spinal diseases in pugs and French bulldogs. [PDF]

Vet Rec
Kerr S, Skovola E, Maskell L, De Decker S.   +3 more
europepmc   +1 more source