Impact of Preoperative Total Knee Arthroplasty on Radiological and Clinical Outcomes of Spinal Fusion for Concurrent Knee Osteoarthritis and Degenerative Lumbar Spinal Diseases. [PDF]
Kim HJ +7 more
europepmc +1 more source
Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh +7 more
wiley +1 more source
Posterior treatment of ankylosing spinal diseases with thoracolumbar fractures: a network meta-analysis. [PDF]
Shi J +5 more
europepmc +1 more source
A Review on the Use of Artificial Intelligence in Spinal Diseases. [PDF]
Azimi P +6 more
europepmc +1 more source
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu +14 more
wiley +1 more source
Incidence Rates and Diagnostic Trends of Perioperative Acute Transverse Myelitis in Patients Who Underwent Surgery for Degenerative Spinal Diseases: A Nationwide Epidemiologic Study of 201,769 Patients. [PDF]
Kim J, Kim TH.
europepmc +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Development and validation of a nomogram prediction model for surgical site infection after instrumentation for degenerative lumbar spinal diseases. [PDF]
Liu Y, Wei X, Chen X, Ding Y.
europepmc +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Medical care for spinal diseases during the COVID-19 pandemic. [PDF]
Silva RTE +3 more
europepmc +1 more source

