Results 61 to 70 of about 10,226,644 (391)

Behavioral Trait of Morningness-Eveningness in Association with Articular and Spinal Diseases in a Population

PLoS ONE, 2014
Earlier studies have revealed that the more the preference to schedule daily activities towards the evening hours is, the higher the odds for a range of health hazards are.
I. Merikanto, T. Lahti, S. Seitsalo, E. Kronholm, T. Laatikainen, Markku Peltonen, E. Vartiainen, T. Partonen   +7 more
semanticscholar   +1 more source

Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]

, 1979
Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin, Grafe, Peter, Ten Bruggencate, Gerrit   +2 more
core   +1 more source

Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS. [PDF]

, 2018
Reactive astrocytes influence post-injury recovery, repair, and pathogenesis of the mammalian CNS. Much of the regulation of astrocyte reactivity, however, remains to be understood.
Carolino, Krislyn I, Chen, Meifan, Elzière, Lucie, Geoffroy, Cédric G, Goldberg, Mark P, Jin, Yishi, Khai, Vung S, Kong, Xiangmei, Li, Yunbo, Meves, Jessica M, Narang, Aarti, Nguyen, Mallorie T, Steinke, Christopher L, Zheng, Binhai   +13 more
core   +2 more sources

Development and validation of a nomogram to predict the unfavorable outcomes in elderly patients undergoing lumbar fusion surgery for degenerative disease

BMC Surgery
Objective Failure to understand long-term quality of life and functional outcomes hinders effective decision making and prognostication. Therefore, the study aims to predict and analyse the unfavorable outcomes (FOs) in elderly patients undergoing lumbar
Peng Cui, Shuaikang Wang, Haojie Zhang, Peng Wang, Xiaolong Chen, Chao Kong, Shibao Lu   +6 more
doaj   +1 more source

A Five-year Study of Spinal Disorders among Patients Presenting to the National Trauma Center of Nepal: An Observational Study

Journal of Nepal Medical Association
Introduction: Spinal cord injuries result in severe neurological impairments and disabilities. With an estimated 15.4 million cases globally in 2021, spinal cord injuries are more common in low- and middle-income countries, yet research in these areas ...
Badri Rijal, Min Chandra Adhikari, Suzit Bhusal, Reshika Shrestha, Ashlesha Chaudhary, Dipendra Pandey, Mandish Prasad Phuyal, Akanshya Prasai, Aashutosh Chaudhary   +8 more
doaj   +1 more source

Adjacent Segment Pathology Following Anterior Decompression and Fusion Using Cage and Plate for the Treatment of Degenerative Cervical Spinal Diseases

Asian Spine Journal, 2014
Study Design Retrospective study. Purpose To analyze the incidence and prevalence of clinical adjacent segment pathology (CASP) following anterior decompression and fusion with cage and plate augmentation for degenerative cervical diseases.
K. Song, Byung-Wan Choi, Jong-Kil Kim
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Defective axonal transport in motor neuron disease [PDF]

, 2007
Several recent studies have highlighted the role of axonal transport in the pathogenesis of motor neuron diseases. Mutations in genes that control microtubule regulation and dynamics have been shown to cause motor neuron degeneration in mice and in a ...
Baas, Blair, Boillee, Bommel, Borchelt, Bowling, Brown, Bruijn, Burger, Cao, Cleveland, Cleveland, Duchen, Escurat, Evans, Fichera, Fliegner, Gaudette, Goldstein, Hadano, Hafezparast, Hazan, Hirokawa, Hirokawa, Hirokawa, Jablonka, Joshi, Kanai, Kaplan, Kieran, King, Kong, LaMonte, Levy, Ligon, Liu, Lo Giudice, Lu, Martin, Miki, Miki, Mitsumoto, Mitsumoto, Muglia, Munch, Nicholson, Nishimura, Okabe, Otomo, Parkinson, Parysek, Pasinelli, Patel, Proukakis, Puls, Puls, Quenneville, Rao, Reid, Reid, Reid, Rosen, Ross, Rowland, Sanderson, Schmitt-John, Shaw, Shibata, Siegel, Song, Teuchert, Troy, Vallee, Weber, Williamson, Wood, Xia, Zhao   +77 more
core   +1 more source

The role of supine imaging in assessing failure of pelvic compensation and its impact on surgical outcomes in patients with adult spinal deformity

Journal of Orthopaedic Surgery and Research
Aims This study aims to investigate the impacts of failure of pelvic compensation (FPC), as determined by variations in spinopelvic alignment during the transition from the supine to the upright position, on surgical outcomes in patients with adult ...
Dongfan Wang, Wei Wang, Yu Wang, Chao Kong, Shuaikang Wang, Xiaolong Chen, Shibao Lu   +6 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source