Results 61 to 70 of about 2,510,109 (253)
A validation of the Oswestry Spinal Risk Index [PDF]
Purpose The purpose of this study was to validate the Oswestry Spinal Risk Index (OSRI) in an external population. The OSRI predicts survival in patients with metastatic spinal cord compression (MSCC).
Saeed, Mohammad +8 more
core +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Adenosine-mediated modulation of ventral horn interneurons and spinal motoneurons in neonatal mice [PDF]
The authors are grateful for support from the Wellcome Trust.Neuromodulation allows neural networks to adapt to varying environmental and biomechanical demands. Purinergic signalling is known to be an important modulatory system in many parts of the CNS,
Witts, Emily Charlotte +3 more
core +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Relation of eye and spinal diseases
RELATION OF EYE AND SPINAL DISEASES Franciscus Cornelius Donders Library (-) Relation of eye and spinal diseases (-
Friedenwald, A.
core +1 more source
Amyloidosis presenting as multiple vertebral fractures
Amyloidosis is a plasma cell disorder characterized by the overproduction and tissue deposition of a monoclonal IG light chain or fragments. Musculoskeletal and soft tissue manifestations are arthropathy, myopathy, bone lesions, and lymphadenopathy.
Ricardo Vieira Botelho +2 more
doaj +1 more source
A functional motor unit in the culture dish : co-culture of spinal cord explants and muscle cells [PDF]
Human primary muscle cells cultured aneurally in monolayer rarely contract spontaneously because, in the absence of a nerve component, cell differentiation is limited and motor neuron stimulation is missing(1). These limitations hamper the in vitro study
Handschin, Christoph +5 more
core +1 more source
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
Spinous process fractures after chiropractic massage in a previously healthy subject
Increasing available alternative therapies to the treatment of back pain and sometimes difficult access to specialized medical evaluations allowed a widespread use of alternative therapies for the treatment of back pain.
Ricardo Vieira Botelho +3 more
doaj +1 more source
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source

